1. Signaling Pathways
  2. MAPK/ERK Pathway
  3. p38 MAPK
  4. p38α Inhibitors

p38α Inhibitors

p38 MAPK

p38α

p38β

MAPK13

p38δ

p38γ

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform p38α together.

Please try each isoform separately.

p38α Specific Inhibitors
Product Name p38α p38 MAPK p38β p38δ p38γ p38α Selectivity Purity
p38α inhibitor 2
p38α MAPK, pIC50: 9.6
        Selective Inhibitor 98.97%
TAK-715
p38α, IC50: 7.1 nM
 
p38β, IC50: 200 nM
p38δ, IC50: >10 μM
p38γ, IC50: >10 μM
Selective Inhibitor 99.89%
Neflamapimod
p38α, IC50: 10 nM
 
p38β, IC50: 220 nM
    Selective Inhibitor ≥98.0%
Talmapimod
p38α, IC50: 9 nM
 
p38β, IC50: 90 nM
    Selective Inhibitor 98.73%
Pamapimod
p38α, IC50: 14 nM
p38α, Ki: 1.3 nM
 
p38β, IC50: 480
p38β, Ki: 120 nM
    Selective Inhibitor 99.92%
BMS-582949 hydrochloride
p38α MAPK, IC50: 13 nM
        Selective Inhibitor 98.82%
MW-150
p38α, Ki: 101 nM
        Selective Inhibitor 99.90%
R1487 Hydrochloride
p38α, Kd: 0.2 nM
 
p38β, Kd: 29 nM
    Selective Inhibitor 98.94%
p38α inhibitor 1
p38α
        Selective Inhibitor 98.70%
SD-169
p38α MAPK, IC50: 3.2 nM
 
p38β MAPK, IC50: 122 nM
    Selective Inhibitor 99.44%
RWJ-67657
p38α, IC50: 1 μM
 
p38β, IC50: 11 μM
    Selective Inhibitor ≥98.0%
AL 8697
p38α, IC50: 6 nM
 
p38β, IC50: 82 nM
    Selective Inhibitor ≥99.0%
SJFδ
p38α, DC50: 46.17 nM
        Selective Inhibitor
MW-150 hydrochloride
p38α, Ki: 101 nM
        Selective Inhibitor
MW-150 dihydrochloride dihydrate
p38α, Ki: 101 nM
        Selective Inhibitor
PF-03715455
p38α, IC50: 0.88 nM
 
p38β, IC50: 23 nM
    Selective Inhibitor
Talmapimod hydrochloride
p38α, IC50: 9 nM
 
p38β, IC50: 90 nM
    Selective Inhibitor
SJFα
p38α, DC50: 7.16 nM
   
p38δ, DC50: 299 nM
  Selective Inhibitor
SB 202190
p38α, IC50: 50 nM
 
p38β2, IC50: 100 nM
    Pan Inhibitor 99.89%
Doramapimod
p38α, IC50: 38 nM
p38 MAP kinase, Kd: 0.1 nM
p38β, IC50: 65 nM
p38δ, IC50: 520 nM
p38γ, IC50: 200 nM
Pan Inhibitor 99.88%
Ralimetinib
p38α MAPK, IC50: 5.3 nM
 
p38β MAPK, IC50: 3.2 nM
    Pan Inhibitor
Ralimetinib dimesylate
p38α MAPK, IC50: 5.3 nM
 
p38β MAPK, IC50: 3.2 nM
    Pan Inhibitor 99.52%
UM-164
p38α
 
p38β
    Pan Inhibitor 99.08%
AMG-548 dihydrochloride
p38α, Ki: 0.5 nM
dog p38α, Ki: 5.0 nM
 
p38β, Ki: 3.6 nM
p38δ, Ki: 2600 nM
p38γ, Ki: 4100 nM
Pan Inhibitor ≥98.0%
SR-318
p38α, IC50: 5 nM
 
p38β, IC50: 32 nM
    Pan Inhibitor 98.87%
AMG-548
p38α, Ki: 0.5 nM
dog p38α, Ki: 5.0 nM
 
p38β, Ki: 3.6 nM
p38δ, Ki: 2600 nM
p38γ, Ki: 4100 nM
Pan Inhibitor ≥99.0%
EW-7195
p38α, IC50: 1.5 μM
        Pan Inhibitor