p38α ligand-1
Based on 1 Customer Validation
P38α ligand-1 is a p38α ligand that can be used for the synthesis of PROTACs, such as NR-7h (HY-153932).
For research use only. We do not sell to patients.
- Purity: 98.94%
- CAS No.: 586379-64-8
- Formula: C21H16BrF2NO4
- Molecular Weight:464.26
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
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p38α |
Chemical Information
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CAS No. 586379-64-8
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Appearance Solid
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Molecular Weight 464.26
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Formula C21H16BrF2NO4
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Color White to off-white
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SMILES
O=C(C1=CC=C(C)C(N2C(C(Br)=C(C=C2C)OCC3=CC=C(C=C3F)F)=O)=C1)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (215.40 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1540 mL | 10.7698 mL | 21.5397 mL | 53.8491 mL |
| 5 mM | 0.4308 mL | 2.1540 mL | 4.3079 mL | 10.7698 mL | |
| 10 mM | 0.2154 mL | 1.0770 mL | 2.1540 mL | 5.3849 mL | |
| 15 mM | 0.1436 mL | 0.7180 mL | 1.4360 mL | 3.5899 mL | |
| 20 mM | 0.1077 mL | 0.5385 mL | 1.0770 mL | 2.6925 mL | |
| 25 mM | 0.0862 mL | 0.4308 mL | 0.8616 mL | 2.1540 mL | |
| 30 mM | 0.0718 mL | 0.3590 mL | 0.7180 mL | 1.7950 mL | |
| 40 mM | 0.0538 mL | 0.2692 mL | 0.5385 mL | 1.3462 mL | |
| 50 mM | 0.0431 mL | 0.2154 mL | 0.4308 mL | 1.0770 mL | |
| 60 mM | 0.0359 mL | 0.1795 mL | 0.3590 mL | 0.8975 mL | |
| 80 mM | 0.0269 mL | 0.1346 mL | 0.2692 mL | 0.6731 mL | |
| 100 mM | 0.0215 mL | 0.1077 mL | 0.2154 mL | 0.5385 mL |