2. PROTAC MAPK/ERK Pathway
  3. PROTACs p38 MAPK
  4. NR-7h

NR-7h is a potent and selective p38α and p38β degrader with DC50 values of 24 nM and 27.2 nM for p38α in T47D, MB-MDA-231 cells, respectively.

For research use only. We do not sell to patients.

NR-7h Chemical Structure

NR-7h Chemical Structure

CAS No. : 2550399-06-7

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NR-7h Related Antibodies

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Description

NR-7h is a potent and selective p38α and p38β degrader with DC50 values of 24 nM and 27.2 nM for p38α in T47D, MB-MDA-231 cells, respectively[1].

Molecular Weight

998.87

Formula

C48H50BrF2N9O8
CAS No.
SMILES

O=C(NCCCCC1=CN(CCCC(NCCCCNC2=CC=CC(C(N3C(CC4)C(NC4=O)=O)=O)=C2C3=O)=O)N=N1)C5=CC=C(C)C(N6C(C)=CC(OCC7=CC=C(F)C=C7F)=C(Br)C6=O)=C5
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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NR-7h Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NR-7h2550399-06-7PROTACsp38 MAPKT47DMB-MDA-231 cellsInhibitorinhibitorinhibit

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