1. Signaling Pathways
  2. PROTAC
  3. PROTACs
  4. PROTACs Inhibitors

PROTACs Inhibitors

von Hippel-Lindau (VHL)

Cereblon

MDM2

cIAP1

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PROTACs Degraders, Inhibitors & Modulators
Product Name von Hippel-Lindau (VHL) Cereblon MDM2 cIAP1 Purity
FKBP12 PROTAC dTAG-13  
Cereblon
    99.75%
DT2216
VHL
      99.97%
dBET1  
Cereblon
    99.24%
dCBP-1  
Cereblon
    99.44%
MD-224    
MDM2, IC50: 1 nM
  98.47%
SD-36  
Cereblon
    98.52%
dTAGV-1 TFA
VHL
      99.92%
TL12-186  
Cereblon
    99.63%
LC-2
VHL
     
BSJ-03-123  
Cereblon
    98.12%
BSJ-4-116  
Cereblon
    98.73%
ZXH-3-26  
Cereblon
    98.90%
ARCC-4
VHL
      99.90%
PROTAC CDK2/9 Degrader-1  
Cereblon
    99.85%
PROTAC-O4I2  
Cereblon
    98.96%
MS4078  
Cereblon
    99.63%
MS67
VHL
      98.73%
PROTAC RIPK degrader-2
VHL
      99.48%
FKBP12 PROTAC dTAG-7  
Cereblon
    99.88%
PROTAC AR-V7 degrader-1
VHL
      99.34%
JB170  
Cereblon
    98.40%
PROTAC K-Ras Degrader-1  
Cereblon
    98.05%
XY028-140  
Cereblon
    98.42%
PROTAC IRAK4 degrader-1  
Cereblon
    99.72%
CP-10  
Cereblon
    98.22%
FKBP12 PROTAC RC32  
Cereblon
    98.58%
INY-03-041  
Cereblon
    98.64%
NX-5948  
Cereblon
    99.33%
JH-XI-10-02  
Cereblon
    99.82%
MS4322
VHL
      98.28%
PROTAC BRD9 Degrader-1  
CRBN-DDB1, IC50: 48.9 nM
    98.30%
SJF620  
Cereblon
    98.98%
GNE-987
VHL
      99.91%
dFKBP-1  
Cereblon
   
BI-3663  
Cereblon
    99.90%
XZ739  
Cereblon
    99.06%
PROTAC PD-1/PD-L1 degrader-1  
Cereblon
    98.35%
ACBI2
VHL, EC50: 7 nM
      99.76%
PROTAC RIPK degrader-6  
Cereblon
    99.97%
PROTAC CRBN Degrader-1
VHL
Cereblon
    99.84%
SJ10542  
Cereblon
    99.92%
PROTAC ERRα Degrader-3
VHL
      98.82%
Homo-PROTAC pVHL30 degrader 1
VHL
      99.83%
PROTAC HSP90 degrader BP3  
Cereblon
    98.56%
MD-222    
MDM2
  99.81%
CRBN-6-5-5-VHL  
Cereblon, DC50: 1.5 nM
    99.98%
PROTAC Bcl-xL degrader-2
VHL
      98.16%
PROTAC EED degrader-1
VHL
      99.56%
MG-277  
Cereblon
    98.66%
ARD-266
VHL
      99.66%
PROTAC MDM2 Degrader-3    
MDM2
 
SIAIS178
VHL
      99.36%
MS170  
CRBN-DDB1
    99.72%
PROTAC CBP/P300 Degrader-1  
Cereblon
    99.18%
MZP-54
VHL
      98.16%
TL13-112  
Cereblon, IC50: 2.4 μM
    98.15%
PROTAC EED degrader-2
VHL
      98.64%
CFT1946  
Cereblon
    99.84%
SR-1114  
Cereblon
    99.04%
MS4077  
Cereblon
    99.49%
PROTAC FKBP Degrader-3
VHL
      99.48%
Homo-PROTAC cereblon degrader 1  
Cereblon
    99.43%
PROTAC RAR Degrader-1      
cIAP1
SJFα
VHL
      99.61%
ZXH-4-130 TFA
VHL
      99.53%
Tz-Thalidomide  
Cereblon
    98.01%
TD-165  
Cereblon, DC50: 20.4 nM
    99.41%
ARD-61
VHL
      99.68%
MS4322 (isomer)
VHL
      99.22%
MI-389  
Cereblon
    99.34%
PROTAC MDM2 Degrader-1    
MDM2
  98.11%
PROTAC MDM2 Degrader-2    
MDM2
 
CCT367766 formic  
CRBN-DDB1, IC50: 490 nM
    98.02%
PROTAC AR Degrader-4 TFA      
cIAP1
PROTAC ERα Degrader-2      
cIAP1
98.88%
GBD-9  
Cereblon
    99.76%
TL13-12  
Cereblon, IC50: 1.2 μM
    98.06%
PROTAC ER Degrader-4
VHL
      98.22%
DP-C-4  
Cereblon
    99.72%
C004019
VHL
      99.37%
OARV-771
VHL
      98.33%
Thalidomide-NH-CBP/p300 ligand 2  
Cereblon
    99.85%
Dovitinib-RIBOTAC  
Cereblon
    98.93%
HDAC6 degrader-3  
Cereblon
    98.60%
PZ703b
VHL
      98.47%
PROTAC AR Degrader-4      
cIAP1
PROTAC PARP1 degrader    
MDM2
  99.32%
INY-03-041 trihydrochloride  
Cereblon
    99.27%
SJF620 hydrochloride  
Cereblon
    99.28%
PROTAC BRD4 Degrader-2  
Cereblon
   
PROTAC ERRα Degrader-2    
MDM2
 
PROTAC BRD2/BRD4 degrader-1  
Cereblon
   
PROTAC Bcl-xL degrader-3
VHL
     
XY-06-007  
Cereblon
   
PROTAC MDM2 Degrader-4    
MDM2
 
PROTAC ERRα Degrader-1    
MDM2
 
PROTAC Bcl-xL degrader-1      
cIAP1
(S)-GNE-987
VHL
     
MS98
VHL
     
SJFδ
VHL
     
CCT367766  
CRBN-DDB1, IC50: 490 nM
   
TD-428  
Cereblon
   
MS33
VHL
     
Abd110  
Cereblon
   
SA-VA
VHL
     
ZXH-4-130
VHL
     
MS8847
VHL
     
SA-PA  
Cereblon
   
PROTAC SMARCA2 degrader-3  
Cereblon
   
UNC9036
VHL
     
NU223612  
Cereblon
   
Nampt degrader-2
VHL
     
MS154  
Cereblon
   
PROTAC SOS1 degrader-3  
Cereblon
   
PROTAC BRAF-V600E degrader-2  
Cereblon
   
PROTAC TG2 degrader-1
VHL
     
RIP2 Kinase Inhibitor 4      
cIAP1