1784751-20-7
1784751-20-7
Chemical Structure
CK1-IN-1
- CAS No.: 1784751-20-7
- Formula:C24H15F2N3
- Molecular Weight:383.39
IUPAC Name: 4-(2-(1-fluoronaphthalen-2-yl)-4-(4-fluorophenyl)-1H-imidazol-5-yl)pyridine
InChIKey: PUQAFIILJICJRR-UHFFFAOYSA-N
SMILES: FC1=CC=C(C2=C(C3=CC=NC=C3)NC(C4=CC=C5C=CC=CC5=C4F)=N2)C=C1
Biological Activity: CK1-IN-1 (Compound 1c) is a casein kinase 1 (CK1) inhibitor with IC50 values of 15 nM and 16 nM for CK1δ and CK1ε, respectively. CK1-IN-1 inhibits p38α MAPK with an IC50 of 73 nM. CK1-IN-1 can be used to study cardiomyogenesis[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CK1-IN-1 | 99.19% | CK1-IN-1 (Compound 1c) is a casein kinase 1 (CK1) inhibitor with IC50 values of 15 nM and 16 nM for CK1δ and CK1ε, respectively. CK1-IN-1 inhibits p38α MAPK with an IC50 of 73 nM. CK1-IN-1 can be used to study cardiomyogenesis. | ||||||||||||||||||||
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CK1-IN-1 (Standard) | ≥98% | CK1-IN-1 (Standard) is the analytical standard of CK1-IN-1 (HY-111820). This product is intended for research and analytical applications. CK1-IN-1 (Compound 1c) is a casein Kinase 1 (CK1) inhibitor with IC50 values of 15 nM and 16 nM for CK1δ and CK1ε, respectively. CK1-IN-1 inhibits p38α MAPK with an IC50 of 73 nM. CK1-IN-1 can be used to study cardiomyogenesis. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.81
HY-100115RTA-02 (Standard) -
Similarity Score 0.75
HY-100114TA-01 -
Similarity Score 0.74
HY-183530p38 MAPK-IN-11 -
Similarity Score 0.74
HY-178209p38 MAP Kinase-IN-3 -
Similarity Score 0.73
HY-10295SB 202190 -
Similarity Score 0.72
HY-10295ARSB 202190 hydrochloride (Standard) -
Similarity Score 0.72
HY-180445Glucagon receptor antagonist-10 -
Similarity Score 0.71
HY-175431p38 MAPK-IN-8 -
Similarity Score 0.71
HY-177156Glucagon receptor antagonist-8 -
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