1. Cell Cycle/DNA Damage
    Stem Cell/Wnt
    MAPK/ERK Pathway
  2. Casein Kinase
    p38 MAPK

TA-01 

Cat. No.: HY-100114 Purity: 96.34%
Data Sheet SDS Handling Instructions

TA-01 potently inhibits CK1ε, CK1δ,and p38α (IC50values are 6.4, 6.8, and 6.7 nM respectively).

For research use only. We do not sell to patients.
TA-01 Chemical Structure

TA-01 Chemical Structure

CAS No. : 1784751-18-3

Size Price Stock Quantity
10 mM * 1 mL in DMSO $132 In-stock
5 mg $120 In-stock
10 mg $180 In-stock
50 mg $720 In-stock
100 mg   Get quote  
200 mg   Get quote  

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Description

TA-01 potently inhibits CK1ε, CK1δ,and p38α (IC50values are 6.4, 6.8, and 6.7 nM respectively). IC50 value: 6.4/6.8/6.7 nM Target: CK1ε/ CK1δ/p38α MAPK in vitro: TA-01 inhibitors inhibit cardiac development when applied at 5 μM. TA-01 shows an almost complete inhibition of cardiogenesis when applied at 5 μM. TA-01 shows reduced expression of all tested mesoderm markers and the pre-cardiac marker Isl-1.

References
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.8464 mL 14.2320 mL 28.4641 mL
5 mM 0.5693 mL 2.8464 mL 5.6928 mL
10 mM 0.2846 mL 1.4232 mL 2.8464 mL
References
M.Wt

351.32

Formula

C₂₀H₁₂F₃N₃

CAS No.

1784751-18-3

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

10 mM in DMSO

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Product Name:
TA-01
Cat. No.:
HY-100114
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