2419700-58-4
Chemical Structure
GluN2B-NMDAR Allosteric modulator 1
- CAS No.: 2419700-58-4
- Formula:C17H21N5
- Molecular Weight:295.38
InChIKey: HMYLOEKXFAWYBB-UHFFFAOYSA-N
SMILES: CC(N1C=CN=C1CNCC2=CC=C(N3C=CN=C3)C=C2)C
Biological Activity: GluN2B-NMDAR Allosteric modulator 1 is a selective GluN2B-NMDAR positive allosteric modulator. GluN2B-NMDAR Allosteric modulator 1 can increase glutamate- and aspartate-evoked GluN2B-NMDAR-gated currents with EC50 values of 43.7 and 18 nM. GluN2B-NMDAR Allosteric modulator 1 can reverse anxiety-like behavior and social cognition deficits in mice. GluN2B-NMDAR Allosteric modulator 1 can be used for the research of neurological disease, such as anxiety[1].
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GluN2B-NMDAR Allosteric modulator 1 | 99.87% | GluN2B-NMDAR Allosteric modulator 1 is a selective GluN2B-NMDAR positive allosteric modulator. GluN2B-NMDAR Allosteric modulator 1 can increase glutamate- and aspartate-evoked GluN2B-NMDAR-gated currents with EC50 values of 43.7 and 18 nM. GluN2B-NMDAR Allosteric modulator 1 can reverse anxiety-like behavior and social cognition deficits in mice. GluN2B-NMDAR Allosteric modulator 1 can be used for the research of neurological disease, such as anxiety. | ||||||||||||||||||||
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Keywords
