L-Phenylalanine-d5
Based on 1 publication(s) in Google Scholar
L-Phenylalanine-d5 is the deuterium labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals.
For research use only. We do not sell to patients.
- Purity: 99.90%
- CAS No.: 56253-90-8
- Formula: C9H6D5NO2
- Molecular Weight:170.22
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) L-Phenylalanine-d5
MoreAll Calcium Channel Isoforms
MoreAll iGluR Isoforms
MoreAll Endogenous Metabolite Isoforms
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Biological Activity
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NMDA Receptor |
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 56253-90-8
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Unlabeled Cas 63-91-2
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Appearance Solid
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Molecular Weight 170.22
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Formula C9H6D5NO2
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Color White to off-white
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SMILES
OC([C@@H](N)CC1=C([2H])C([2H])=C([2H])C([2H])=C1[2H])=O
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Synonyms
(S)-2-Amino-3-phenylpropionic acid-d5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications (1)
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Journal Impact Factor
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Most Recent
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ACS Cent Sci
Chlorquinaldol Alleviates Lung Fibrosis in Mice by Inhibiting Fibroblast Activation through Targeting Methionine Synthase Reductase. [Abstract]2024 Aug 28;10(9):1789-1802. PMID: 39345816
Solvent & Solubility
H2O : 12.5 mg/mL (73.43 mM; ultrasonic and warming and heat to 60°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 5.8748 mL | 29.3738 mL | 58.7475 mL | 146.8688 mL |
| 5 mM | 1.1750 mL | 5.8748 mL | 11.7495 mL | 29.3738 mL | |
| 10 mM | 0.5875 mL | 2.9374 mL | 5.8748 mL | 14.6869 mL | |
| 15 mM | 0.3917 mL | 1.9583 mL | 3.9165 mL | 9.7913 mL | |
| 20 mM | 0.2937 mL | 1.4687 mL | 2.9374 mL | 7.3434 mL | |
| 25 mM | 0.2350 mL | 1.1750 mL | 2.3499 mL | 5.8748 mL | |
| 30 mM | 0.1958 mL | 0.9791 mL | 1.9583 mL | 4.8956 mL | |
| 40 mM | 0.1469 mL | 0.7343 mL | 1.4687 mL | 3.6717 mL | |
| 50 mM | 0.1175 mL | 0.5875 mL | 1.1750 mL | 2.9374 mL | |
| 60 mM | 0.0979 mL | 0.4896 mL | 0.9791 mL | 2.4478 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
L-Phenylalanine-d5 Related Classifications
HY-N0215S12 Related Classifications
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