2. Signaling Pathways
  3. Membrane Transporter/Ion Channel
    Neuronal Signaling
  4. iGluR
  5. NMDA Receptor Isoform
  6. NMDA Receptor Modulator

NMDA Receptor Modulator

NMDA Receptor Modulators (5):

Cat. No. Product Name Effect Purity
  • HY-135741
    NYX-2925
    		Modulator 98.77%
    NYX-2925 is an orally active NMDAR modulator. NYX-2925 restores levels of activated Src and Src phosphorylation sites on GluN2A and GluN2B in the mPFC. NYX-2925 shows no effect on CAMKII, and any addictive or sedative/ataxic side effects. NYX-2925 can be used for research of a variety of NMDA receptor-mediated central nervous system disorders.
  • HY-N0204
    Pulchinenoside A
    		Modulator ≥98.0%
    Pulchinenoside A is a natural triterpenoid saponin that enhances synaptic plasticity in the adult mouse hippocampus and facilitates spatial memory in adult mice.
  • HY-147260
    Dalzanemdor
    		Modulator
    Dalzanemdor (SAGE-718) is a N-methyl-D-aspartate (NMDA) receptor positive allosteric modulator.
  • HY-147352
    NMDA receptor potentiator-1
    		Modulator
    NMDA receptor potentiator-1 (Compound 1368) is a subunit selective NMDA receptor potentiator with IC50s of 4 μM and 5 μM against NR2C and NR2D expression, respectively.
  • HY-100667
    UBP608
    		Modulator 99.60%
    UBP608 is a potent N-Methyl-D-aspartate receptors (NMDARs) negative allosteric modulator. UBP608 has the potential for the research of neurological disorders.