1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Creatinine

Creatinine (Synonyms: NSC13123)

Cat. No.: HY-B0504 Purity: 99.87%
Handling Instructions

Creatinine(NSC13123) is a break-down product of creatine phosphate in muscle, and is usually produced at a fairly constant rate by the body.

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Creatinine Chemical Structure

Creatinine Chemical Structure

CAS No. : 60-27-5

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10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
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Based on 2 publication(s) in Google Scholar

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Description

Creatinine(NSC13123) is a break-down product of creatine phosphate in muscle, and is usually produced at a fairly constant rate by the body. Target: Others Creatinine is a breakdown product of creatine phosphate in muscle, and is usually produced at a fairly constant rate by the body (depending on muscle mass). Creatine is synthesized primarily in the liver from the methylation of glycocyamine (guanidino acetate, synthesized in the kidney from the amino acids arginine and glycine) by S-adenosyl methionine. It is then transported through blood to the other organs, muscle, and brain, where, through phosphorylation, it becomes the high-energy compound phosphocreatine. During the reaction, creatine and phosphocreatine are catalyzed by creatine kinase, and a spontaneous conversion to creatinine may occur [1]. Creatinine levels in blood and urine may be used to calculate the creatinine clearance (CrCl), which reflects the glomerular filtration rate (GFR), an important clinical index of renal function [2].

Clinical Trial
Molecular Weight

113.12

Formula

C4H7N3O

CAS No.
SMILES

O=C1N=C(N)N(C)C1

Structure Classification
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 33.33 mg/mL (294.64 mM; Need ultrasonic)

DMSO : 2.5 mg/mL (22.10 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 8.8402 mL 44.2008 mL 88.4017 mL
5 mM 1.7680 mL 8.8402 mL 17.6803 mL
10 mM 0.8840 mL 4.4201 mL 8.8402 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Creatinine
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HY-B0504
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