UBP608
Based on 1 publication(s) in Google Scholar
UBP608 is a potent N-Methyl-D-aspartate receptors (NMDARs) negative allosteric modulator. UBP608 has the potential for the research of neurological disorders.
For research use only. We do not sell to patients.
- Purity: 99.60%
- CAS No.: 2199-87-3
- Formula: C10H5BrO4
- Molecular Weight:269.05
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Publications Citing Use of MedChemExpress (MCE) UBP608
MoreAll iGluR Isoforms
More
Biological Activity
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NMDA Receptor |
UBP608 (100 µM) shows inhibitory activity with the inhibition rate of 89.3%, 63.5%, 56.1%, 23.6% for GluN1/GluN2A, GluN1/GluN2B, GluN1/GluN2C, GluN1/GluN2D, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2199-87-3
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Appearance Solid
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Molecular Weight 269.05
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Formula C10H5BrO4
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Color White to light yellow
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SMILES
O=C(C1=CC2=CC(Br)=CC=C2OC1=O)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Anal Chem
Exposome-Scale Investigation of Cl-/Br-Containing Chemicals Using High-Resolution Mass Spectrometry, Multistage Machine Learning, and Cloud Computing. [Abstract]2025 Jun 3;97(21):11099-11109. PMID: 40401576
Solvent & Solubility
DMSO : 250 mg/mL (929.20 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.7168 mL | 18.5839 mL | 37.1678 mL | 92.9195 mL |
| 5 mM | 0.7434 mL | 3.7168 mL | 7.4336 mL | 18.5839 mL | |
| 10 mM | 0.3717 mL | 1.8584 mL | 3.7168 mL | 9.2920 mL | |
| 15 mM | 0.2478 mL | 1.2389 mL | 2.4779 mL | 6.1946 mL | |
| 20 mM | 0.1858 mL | 0.9292 mL | 1.8584 mL | 4.6460 mL | |
| 25 mM | 0.1487 mL | 0.7434 mL | 1.4867 mL | 3.7168 mL | |
| 30 mM | 0.1239 mL | 0.6195 mL | 1.2389 mL | 3.0973 mL | |
| 40 mM | 0.0929 mL | 0.4646 mL | 0.9292 mL | 2.3230 mL | |
| 50 mM | 0.0743 mL | 0.3717 mL | 0.7434 mL | 1.8584 mL | |
| 60 mM | 0.0619 mL | 0.3097 mL | 0.6195 mL | 1.5487 mL | |
| 80 mM | 0.0465 mL | 0.2323 mL | 0.4646 mL | 1.1615 mL | |
| 100 mM | 0.0372 mL | 0.1858 mL | 0.3717 mL | 0.9292 mL |
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