1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Quinolinic acid

Quinolinic acid 

Cat. No.: HY-100807 Purity: 99.81%
Handling Instructions

Quinolinic acid is an endogenous N-methyl-D-aspartate receptor agonist synthesized from L-tryptophan via the kynurenine pathway and thereby has the potential of mediating N-methyl-D-aspartate neuronal damage and dysfunction.

For research use only. We do not sell to patients.

Quinolinic acid Chemical Structure

Quinolinic acid Chemical Structure

CAS No. : 89-00-9

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
1 g USD 50 In-stock
Estimated Time of Arrival: December 31
5 g   Get quote  
10 g   Get quote  

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Description

Quinolinic acid is an endogenous N-methyl-D-aspartate receptor agonist synthesized from L-tryptophan via the kynurenine pathway and thereby has the potential of mediating N-methyl-D-aspartate neuronal damage and dysfunction.

IC50 & Target

Human Endogenous Metabolite

 

Molecular Weight

167.12

Formula

C₇H₅NO₄

CAS No.

89-00-9

SMILES

O=C(C1=NC=CC=C1C(O)=O)O

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 33.33 mg/mL (199.44 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.9837 mL 29.9186 mL 59.8372 mL
5 mM 1.1967 mL 5.9837 mL 11.9674 mL
10 mM 0.5984 mL 2.9919 mL 5.9837 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (14.96 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (14.96 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (14.96 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: 99.81%

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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Product Name:
Quinolinic acid
Cat. No.:
HY-100807
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