Quinolinic acid-13C4,15N
Based on 1 Customer Validation
Quinolinic acid-13C4, 15N is an isotopic labeled Quinolinic acid (HY-100807). Quinolinic acid, an endogenous metabolite of tryptophan, is a N-methyl-D-aspartate receptor (NMDA receptor) agonist. Quinolinic acid increases glutamate efflux, induces the generation of ROS, activates nitric oxide synthase, produces excessive NO, leading to calcium ion influx and neuronal apoptosis.
For research use only. We do not sell to patients.
- Purity: 98.80%
- Formula: C313C4H515NO4
- Molecular Weight:172.08
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 89-00-9
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Appearance Solid
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Molecular Weight 172.08
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Formula C313C4H515NO4
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Color Off-white to light yellow
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SMILES
O=[13C]([13C]1=[15N]C=CC=[13C]1[13C](O)=O)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 33.33 mg/mL (193.69 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (251 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.8113 mL | 29.0563 mL | 58.1125 mL | 145.2813 mL |
| 5 mM | 1.1623 mL | 5.8113 mL | 11.6225 mL | 29.0563 mL | |
| 10 mM | 0.5811 mL | 2.9056 mL | 5.8113 mL | 14.5281 mL | |
| 15 mM | 0.3874 mL | 1.9371 mL | 3.8742 mL | 9.6854 mL | |
| 20 mM | 0.2906 mL | 1.4528 mL | 2.9056 mL | 7.2641 mL | |
| 25 mM | 0.2325 mL | 1.1623 mL | 2.3245 mL | 5.8113 mL | |
| 30 mM | 0.1937 mL | 0.9685 mL | 1.9371 mL | 4.8427 mL | |
| 40 mM | 0.1453 mL | 0.7264 mL | 1.4528 mL | 3.6320 mL | |
| 50 mM | 0.1162 mL | 0.5811 mL | 1.1623 mL | 2.9056 mL | |
| 60 mM | 0.0969 mL | 0.4843 mL | 0.9685 mL | 2.4214 mL | |
| 80 mM | 0.0726 mL | 0.3632 mL | 0.7264 mL | 1.8160 mL | |
| 100 mM | 0.0581 mL | 0.2906 mL | 0.5811 mL | 1.4528 mL |
Quinolinic acid-13C4,15N Related Classifications
HY-100807S2 Related Classifications
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