Quinolinic acid-¹³C₄,¹⁵N

Name: Quinolinic acid- 13 C 4 , 15 N
Brand: MedChemExpress
SKU: HY-100807S2
Rating: 4.5 (1 reviews)

Cat. No.: HY-100807S2 Purity: 98.80%: Data Sheet
COA

SDS
Handling Instructions
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Quinolinic acid-13C4, 15N is an isotopic labeled Quinolinic acid (HY-100807). Quinolinic acid, an endogenous metabolite of tryptophan, is a N-methyl-D-aspartate receptor (NMDA receptor) agonist. Quinolinic acid increases glutamate efflux, induces the generation of ROS, activates nitric oxide synthase, produces excessive NO, leading to calcium ion influx and neuronal apoptosis.

For research use only. We do not sell to patients.

Quinolinic acid-<sup>13</sup>C<sub>4</sub>,<sup>15</sup>N

Quinolinic acid-¹³C₄,¹⁵N Chemical Structure

Size	Stock	Quantity
100 μg	In-stock	Estimated Time of Arrival: December 31
500 μg	In-stock	Estimated Time of Arrival: December 31
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	Get quote
10 mg	Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Quinolinic acid-¹³C₄,¹⁵N:

Quinolinic acid In-stock

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nNOS iNOS eNOS

Biological Activity
Purity & Documentation
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Description

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

172.08

Formula

C₃¹³C₄H₅¹⁵NO₄

Unlabeled CAS

89-00-9

Appearance

Solid

Color

Off-white to light yellow

SMILES

O=[13C]([13C]1=[15N]C=CC=[13C]1[13C](O)=O)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 33.33 mg/mL (193.69 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.8113 mL	29.0563 mL	58.1125 mL
5 mM	1.1623 mL	5.8113 mL	11.6225 mL
10 mM	0.5811 mL	2.9056 mL	5.8113 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Concentration _(final)

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In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.80%

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Data Sheet (251 KB) SDS (252 KB)

COA (255 KB) LCMS (1153 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	5.8113 mL	29.0563 mL	58.1125 mL	145.2813 mL
	5 mM	1.1623 mL	5.8113 mL	11.6225 mL	29.0563 mL
	10 mM	0.5811 mL	2.9056 mL	5.8113 mL	14.5281 mL
	15 mM	0.3874 mL	1.9371 mL	3.8742 mL	9.6854 mL
	20 mM	0.2906 mL	1.4528 mL	2.9056 mL	7.2641 mL
	25 mM	0.2325 mL	1.1623 mL	2.3245 mL	5.8113 mL
	30 mM	0.1937 mL	0.9685 mL	1.9371 mL	4.8427 mL
	40 mM	0.1453 mL	0.7264 mL	1.4528 mL	3.6320 mL
	50 mM	0.1162 mL	0.5811 mL	1.1623 mL	2.9056 mL
	60 mM	0.0969 mL	0.4843 mL	0.9685 mL	2.4214 mL
	80 mM	0.0726 mL	0.3632 mL	0.7264 mL	1.8160 mL
	100 mM	0.0581 mL	0.2906 mL	0.5811 mL	1.4528 mL