68-41-7
68-41-7
Chemical Structure
D-Cycloserine
- CAS No.: 68-41-7
- Formula:C3H6N2O2
- Molecular Weight:102.09
IUPAC Name: (R)-4-aminoisoxazolidin-3-one
InChIKey: DYDCUQKUCUHJBH-UWTATZPHSA-N
SMILES: O=C1[C@H](N)CON1
Biological Activity: D-Cycloserine is an antibiotic which targets sequential bacterial cell wall peptidoglycan biosynthesis enzymes, with blood-brain barrier permeability. D-Cycloserine is a partial NMDA agonist that can improve cognitive functions. D-Cycloserine can be used for multidrug-resistant tuberculosis research[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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D-Cycloserine | 99.73% | D-Cycloserine is an antibiotic which targets sequential bacterial cell wall peptidoglycan biosynthesis enzymes, with blood-brain barrier permeability. D-Cycloserine is a partial NMDA agonist that can improve cognitive functions. D-Cycloserine can be used for multidrug-resistant tuberculosis research. | ||||||||||||||||||||
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D-Cycloserine (Standard) | 98.38% | D-Cycloserine (Standard) is the analytical standard of D-Cycloserine. This product is intended for research and analytical applications. D-Cycloserine is an antibiotic which targets sequential bacterial cell wall peptidoglycan biosynthesis enzymes. D-Cycloserine is a partial NMDA agonist that can improve cognitive functions. D-Cycloserine can be used for multidrug-resistant tuberculosis research. | ||||||||||||||||||||
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(S)-(-)-HA 966 | (S)-(-)-HA 966 ((-)-HA 966), a γ-Hydroxybutyrate-like agent, is weakly active as an NMDA-receptor antagonist. (S)-(-)-HA 966 possesses muscle relaxant action and prevents enhanced mesocorticolimbic dopamine metabolism and behavioral correlates of restraint stress, conditioned fear. | |||||||||||||||||||||
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(R)-(+)-HA-966 (Standard) | ≥98% | (R)-(+)-HA-966 (Standard) is the analytical standard of (R)-(+)-HA-966 (HY-100822). This product is intended for research and analytical applications. (R)-(+)-HA-966 ((+)-HA-966) is a partial agonist/antagonist of glycine site of the N-methyl-D-aspartate (NMDA) receptor complex. (R)-(+)-HA-966 selectively blocks the activation of the mesolimbic dopamine system by amphetamine. (R)-(+)-HA-966 can cross the blood-brain barrier and has the potential for neuropathic and acute pain. | ||||||||||||||||||||
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3-Amino-2-piperidinone | 99.87% | 3-Amino-2-piperidinone (Cyclo-ornithine) is a cyclic ornithine analogue and can be used as drug intermediate. | ||||||||||||||||||||
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L-Cycloserine | 98.84% | L-Cycloserine ((S)-4-Amino-3-isoxazolidone) is an oral inhibitor of the enzyme gamma-aminobutyric acid (GABA) transaminase (GABA-t) and branched-chain transaminases in Mycobacterium tuberculosis. L-Cycloserine has anticonvulsant properties and inhibits the synthesis of neurotensin in mouse brains. | ||||||||||||||||||||
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L-Orinithine lactam hydrochloride | 97.0% | L-Orinithine lactam hydrochloride is a synthetic intermediate. L-Orinithine lactam (hydrochloride) can be used in the synthesis of dipeptidyl peptidase 4 (DPP-4) inhibitors, as well as signaling peptides. | ||||||||||||||||||||
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(S)-3-Aminopiperidin-2-one (Standard) | ≥98% | L-Orinithine lactam (Standard) is the analytical standard of L-Orinithine lactam. This product is intended for research and analytical applications. L-Orinithine lactam is a synthetic intermediate. L-Orinithine lactam can be used in the synthesis of dipeptidyl peptidase 4 (DPP-4) inhibitors, as well as signaling peptides. | ||||||||||||||||||||
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DL-Cycloserine | DL-Cycloserine is an orally active aminotransferase inhibitor. DL-Cycloserine exhibits completely opposite effects on the activity of monoamine oxidase in different tissues. DL-Cycloserine can be used for the research of pulmonary tuberculosis, psychosomatic diseases, and depressive states. | |||||||||||||||||||||
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(R)-3-Aminopiperidin-2-one | (R)-3-Aminopiperidin-2-one (D-Ornithine lactam) is the building block, that could be used as for synthesis of antibacterial agent or various modulators, such as allosteric HCV NS5B inhibitors. | |||||||||||||||||||||
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(R)-3-Aminopyrrolidine-2,5-dione | (R)-3-Aminopyrrolidine-2,5-dione is a potential anticonvulsant agent and its derivatives have comparable in vivo efficacy. | |||||||||||||||||||||
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(S)-3-Aminopyrrolidine-2,5-dione | (S)-3-Aminopyrrolidine-2,5-dione is a potential anticonvulsant agent and its derivatives have comparable in vivo potency. | |||||||||||||||||||||
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References
- [1]. Nitsche, M.A., et al., Consolidation of human motor cortical neuroplasticity by D-cycloserine. Neuropsychopharmacology, 2004. 29(8): p. 1573-8. [Content Brief]
- [2]. Sarah Batson, et al. Inhibition of D-Ala:D-Ala ligase through a phosphorylated form of the antibiotic D-cycloserine. Nat Commun. 2017 Dec 5;8(1):1939. [Content Brief]
