58-73-1
58-73-1
Chemical Structure
Diphenhydramine
- CAS No.: 58-73-1
- Formula:C17H21NO
- Molecular Weight:255.35
IUPAC Name: 2-(benzhydryloxy)-N,N-dimethylethan-1-amine
InChIKey: ZZVUWRFHKOJYTH-UHFFFAOYSA-N
SMILES: CN(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2
Biological Activity: Diphenhydramine is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB) [1][2][3].
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Diphenhydramine | 99.85% | Diphenhydramine is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB) . | ||||||||||||||||||||
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Diphenhydramine (Standard) | 98.69% | Diphenhydramine (Standard) is the analytical standard of Diphenhydramine. This product is intended for research and analytical applications. Diphenhydramine is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB) . | ||||||||||||||||||||
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References
- [1]. Jason P Berninger, et al. Effects of the antihistamine diphenhydramine on selected aquatic organisms. Environ Toxicol Chem. 2011 Sep;30(9):2065-72. [Content Brief]
- [2]. Föhr KJ, et al. Open channel block of NMDA receptors by diphenhydramine. Neuropharmacology. 2015 Dec;99:459-70. [Content Brief]
- [3]. Ehling S, et al. Diphenhydramine pharmacokinetics after oral and intravenous administration of diphenhydramine and oral administration of dimenhydrinate to healthy dogs, and pharmacodynamic effect on histamine-induced wheal formation: a pilot study. Vet Dermatol. 2019 Apr;30(2):91-e24. [Content Brief]
