1. GPCR/G Protein
  2. Glucagon Receptor
  3. Tirzepatide (TFA)

Tirzepatide (TFA) (Synonyms: LY3298176 (TFA))

Cat. No.: HY-P1731A
Handling Instructions

Tirzepatide TFA (LY3298176 TFA) is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist that is being developed for the treatment of type 2 diabetes.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Tirzepatide (TFA) Chemical Structure

Tirzepatide (TFA) Chemical Structure

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Description

Tirzepatide TFA (LY3298176 TFA) is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist that is being developed for the treatment of type 2 diabetes[1].

IC50 & Target

Glucose-dependent insulinotropic polypeptide (GIP), GLP-1 receptor[1]

Molecular Weight

4927.47

Formula

C₂₂₇H₃₄₉F₃N₄₈O₇₀

Sequence

Tyr-{Aib}-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-{Aib}-Leu-Asp-Lys-Ile-Ala-Gln-Lys-{diacid-gamma-Glu-(AEEA)2-Lys}-Ala-Phe-Val-Gln-Trp-Leu-Ile-Ala-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2

Sequence Shortening

Y-{Aib}-EGTFTSDYSI-{Aib}-LDKIAQ-{diacid-gamma-Glu-(AEEA)2-Lys}-AFVQWLIAGGPSSGAPPPS-NH2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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This equation is commonly abbreviated as: C1V1 = C2V2

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Tirzepatide (TFA)
Cat. No.:
HY-P1731A
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