Pancreastatin (33-49), porcine
Pancreastatin (33-49), porcine is a pancreastatin fragment. Pancreastatin is a peptide isolated from porcine pancreas which has insulin-suppressive actions in vitro. Pancreastatin (33-49), porcine enhances the priming effect of glucose.
For research use only. We do not sell to patients.
- CAS No.: 106507-61-3
- Formula: C77H119N23O30
- Molecular Weight:1846.90
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Chemical Information
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CAS No. 106507-61-3
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Molecular Weight 1846.90
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Formula C77H119N23O30
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Sequence Shortening
QEEEEETAGAPQGLFRG-NH2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Research Protocol for Endocrine Diseases
Endocrine diseases often arise from disrupted hormone production, hormone signaling, or target-tissue responsiveness; for diabetes-focused endocrine disease models, insulin signaling regulates glucose uptake, hepatic glucose output, lipid metabolism, and β-cell compensation. Type 2 diabetes develops through interacting defects in insulin resistance, β-cell dysfunction, adipose inflammation, hepatic glucose overproduction, altered incretin signaling, and ectopic lipid metabolism. A major unresolved question is whether endocrine dysfunction is driven primarily by target-tissue insulin resistance, intrinsic β-cell failure, immune/inflammatory stress, or combined multi-organ failure that differs by disease stage.
Purity & Documentation
References
[1]. Holst JJ, et al. Porcine pancreastatin has no effect on endocrine secretion from the pig pancreas. Diabetologia. 1990 Jul;33(7):403-6. [Content Brief]
[2]. Sánchez-Margalet V, et al. Pancreastatin (33-49) enhances the priming effect of glucose in the rat pancreas. Experientia. 1993 Jul 5;49(6-7):551-2. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pancreastatin (33-49), porcine Related Classifications
HY-P3865 Related Classifications
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