1. Cell Cycle/DNA Damage
  2. PPAR
  3. Fmoc-leucine-d3

Fmoc-leucine-d3 (Synonyms: N-FMOC-leucine-d3; NPC 15199-d3; NSC 334290-d3)

Cat. No.: HY-101064S2
Handling Instructions

Fmoc-leucine-d3 is the deuterium labeled Fmoc-leucine. Fmoc-leucine is a selective PPARγ modulator. Fmoc-leucine activates PPARγ with a lower potency but a similar maximal efficacy than rosiglitazone. Fmoc-leucine improves insulin sensitivity in normal, diet-induced glucose-intolerant, and in diabetic db/db mice. Fmoc-leucine has a lower adipogenic activity.

For research use only. We do not sell to patients.

Fmoc-leucine-d3 Chemical Structure

Fmoc-leucine-d3 Chemical Structure

CAS No. : 538372-74-6

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Description

Fmoc-leucine-d3 is the deuterium labeled Fmoc-leucine. Fmoc-leucine is a selective PPARγ modulator. Fmoc-leucine activates PPARγ with a lower potency but a similar maximal efficacy than rosiglitazone. Fmoc-leucine improves insulin sensitivity in normal, diet-induced glucose-intolerant, and in diabetic db/db mice. Fmoc-leucine has a lower adipogenic activity[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

356.43

Formula

C21H20D3NO4

CAS No.
SMILES

[2H]C([2H])([2H])C(C)C[[email protected]@H](C(O)=O)NC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
Fmoc-leucine-d3
Cat. No.:
HY-101064S2
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