Insulin-Transferrin-Selenium, 100X
Based on 10 publication(s) in Google Scholar
Insulin-Transferrin-Selenium, 100X (ITS-G) is a mixture of Insulin, transferrin, and sodium selenite that is a general supplement designed for use in classic media such as DMEM, RPMI-1640, and nutrient media such as Ham's F-12, DMEM/F-12. Insulin-Transferrin-Selenium is added to basal medium to reduce the amount of fetal calf serum required to culture cells.
For research use only. We do not sell to patients.
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Storage:
Solution, -20°C, 2 years
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Insulin-Transferrin-Selenium, 100X
More- J Adv Res. 2025 Jul 12:S2090-1232(25)00545-4. [Abstract]
- Theranostics. 2025 Aug 16;15(17):9131-9158. [Abstract]
- Adv Sci (Weinh). 2025 Nov 21:e08472. [Abstract]
- Phytomedicine. 2026 Aug:158:158403. [Abstract]
- J Agric Food Chem. 2026 Apr 22;74(15):12069-12086. [Abstract]
- FASEB J. 2026 Feb 28;40(4):e71557. [Abstract]
- J Funct Foods. 2024 Oct.
- Animal Model Exp Med. 2026 Jun 16. [Abstract]
- J Assist Reprod Genet. 2024 Nov;41(11):3189-3200. [Abstract]
- Res Sq. 2025 Jul 21.
Biological Activity
Insulin-Transferrin-Selenium, 100X (1%) can be supplement for DMEM/F12 medium together with 10% FBS, 1% Penicillin/Streptomycin (HY-B1906) and 40 ng/mL Dexamethasone (HY-14648) to culture AML-12 hepatocyte cells[1].
Insulin-Transferrin-Selenium, 100X (4 mL/L) is added to supplement F12 medium together with 5 g/L D-glucose (HY-B0389), 10 mM HEPES (HY-D0857), 7.5 mM L-glutamine (HY-N0390), and 1% FBS to culture HEK293 EBNA cells and CHO-s cells[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Liquid
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Color Colorless to light yellow
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SMILES
[Insulin-Transferrin-Selenium, 100X]
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Synonyms
ITS-G
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Solution, -20°C, 2 years
Publications (10)
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Journal Impact Factor
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Most Recent
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J Adv Res
SIRT7 facilitates ferroptosis resistance of melanocytes via activating the SMAD3-ATF3-GPX4 signaling pathway in vitiligo. [Abstract]2025 Jul 12:S2090-1232(25)00545-4. PMID: 40659088 -
Theranostics
Nanotuner targeting mitochondrial redox and iron homeostasis imbalance for the treatment of acute liver injury. [Abstract]2025 Aug 16;15(17):9131-9158. PMID: 40963901 -
Adv Sci (Weinh)
Targeted Inhibition of CD74+ Macrophages by Luteolin via CEBPB/P65 Signaling Ameliorates Osteoarthritis Progression. [Abstract]2025 Nov 21:e08472. PMID: 41268703 -
Phytomedicine
Sweroside attenuates heart failure with preserved ejection fraction via targeting PCSK9-CD36 interaction to reduce cardiac-hepatic lipotoxicity. [Abstract]2026 Aug:158:158403. PMID: 42287816 -
J Agric Food Chem
Vitamin D 3 Metabolite-Enhanced Hepatic VDR-FXR Binding Attenuates Bile Acid Dysregulation-Induced Diarrhea in Weaned Piglets. [Abstract]2026 Apr 22;74(15):12069-12086. PMID: 41952052 -
FASEB J
Integrated Transcriptomic and Metabolomic Analyses Reveal the Protective Mechanism of Icaritin Against High-Fat Diet-Induced Metabolic Dysfunction-Associated Steatotic Liver Disease in Mice. [Abstract]2026 Feb 28;40(4):e71557. PMID: 41665239 -
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Animal Model Exp Med
IRF-1 modulates hepatic ferroptosis and aggravates liver ischemia/reperfusion injury via DYRK1α. [Abstract]2026 Jun 16. PMID: 42299064 -
J Assist Reprod Genet
High concentration of estrogen resulted by COH may affect the secretion of pro-angiogenic factors in uNK cells by downregulating the expression of IL-11 in decidual stromal cells. [Abstract]2024 Nov;41(11):3189-3200. PMID: 39276273 -
Solvent & Solubility
H2O : ≥ 100 mg/mL
* "≥" means soluble, but saturation unknown.
Purity & Documentation
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Data Sheet (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Wei, M., et al., (2022). Hepatocyte-Specific Smad4 Deficiency Alleviates Liver Fibrosis via the p38/p65 Pathway. International journal of molecular sciences, 23(19), 11696. [Content Brief]
[2]. Croset, A., et al., (2012). Differences in the glycosylation of recombinant proteins expressed in HEK and CHO cells. Journal of biotechnology, 161(3), 336–348. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Insulin-Transferrin-Selenium, 100X Related Classifications
HY-150287 Related Classifications
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