1. Protein Tyrosine Kinase/RTK
  2. IGF-1R
  3. IGF-1R inhibitor-2

IGF-1R inhibitor-2 

Cat. No.: HY-145110
Handling Instructions

IGF-1R inhibitor-2 (example 121) is an insulin-like growth factor-1 receptor (IGF-1R) inhibitor. Downregulation of IGF-1R can reverse the transformed phenotype of tumor cells and potentially render them susceptible to apoptosis.

For research use only. We do not sell to patients.

IGF-1R inhibitor-2 Chemical Structure

IGF-1R inhibitor-2 Chemical Structure

CAS No. : 1116236-15-7

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Description

IGF-1R inhibitor-2 (example 121) is an insulin-like growth factor-1 receptor (IGF-1R) inhibitor. Downregulation of IGF-1R can reverse the transformed phenotype of tumor cells and potentially render them susceptible to apoptosis[1].

IC50 & Target[1]

IGF-1R

 

Molecular Weight

461.49

Formula

C24H24FN7O2

CAS No.
SMILES

O=C(C1=C(NC2=C3C=CNC3=NC(NC4=C(OC)C=C(CCN(C5)C)C5=C4)=N2)C=CC=C1F)N

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Product Name:
IGF-1R inhibitor-2
Cat. No.:
HY-145110
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