1116236-15-7
Chemical Structure
IGF-1R inhibitor-2
- CAS No.: 1116236-15-7
- Formula:C24H24FN7O2
- Molecular Weight:461.49
IUPAC Name: 2-fluoro-6-((2-((6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)benzamide
InChIKey: FDCFRUWNFPYFBR-UHFFFAOYSA-N
SMILES: O=C(C1=C(NC2=C3C=CNC3=NC(NC4=C(OC)C=C(CCN(C5)C)C5=C4)=N2)C=CC=C1F)N
Biological Activity: IGF-1R inhibitor-2 (example 121) is an insulin-like growth factor-1 receptor (IGF-1R) inhibitor. Downregulation of IGF-1R can reverse the transformed phenotype of tumor cells and potentially render them susceptible to apoptosis[1].
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IGF-1R inhibitor-2 | 98.07% | IGF-1R inhibitor-2 (example 121) is an insulin-like growth factor-1 receptor (IGF-1R) inhibitor. Downregulation of IGF-1R can reverse the transformed phenotype of tumor cells and potentially render them susceptible to apoptosis. | ||||||||||||||||||||
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Keywords