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ML-290 

Cat. No.: HY-112606
Handling Instructions

ML-290 is a potent and orally active relaxin/insulin-like family peptide receptor (RXFP1) agonist and activator of anti-fibrotic genes, with an EC50 of 94 nM.

For research use only. We do not sell to patients.

ML-290 Chemical Structure

ML-290 Chemical Structure

CAS No. : 1482500-76-4

Size Price Stock
5 mg USD 160 Get quote
10 mg USD 260 Get quote

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Customer Review

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

ML-290 is a potent and orally active relaxin/insulin-like family peptide receptor (RXFP1) agonist and activator of anti-fibrotic genes, with an EC50 of 94 nM[1].

IC50 & Target

EC50: 94 nM (RXFP1)[1]

In Vitro

ML-290 is a potent and orally active relaxin/insulin-like family peptide receptor (RXFP1) agonist and activator of anti-fibrotic genes, with an EC50 of 94 nM[1].
ML290 (5 μM) shows anti-fibrotic, relaxin-like gene expression at 24 and 72 h in activated human hepatic stellate cells[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9744 mL 9.8719 mL 19.7437 mL
5 mM 0.3949 mL 1.9744 mL 3.9487 mL
10 mM 0.1974 mL 0.9872 mL 1.9744 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

506.49

Formula

C₂₄H₂₁F₃N₂O₅S

CAS No.

1482500-76-4

SMILES

O=C(NC1=CC(S(=O)(C(F)(F)F)=O)=CC=C1)C2=C(NC(C3=CC=CC=C3OC(C)C)=O)C=CC=C2

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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Product Name:
ML-290
Cat. No.:
HY-112606
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ML-290

Cat. No.: HY-112606