2. Antibodies
  3. Primary Antibodies
  4. Monoclonal Antibodies Recombinant Antibodies
  5. Insulin Receptor Antibody (YA340)

Insulin Receptor Antibody (YA340)

Cat. No.: HY-P80193
User Guide for Antibodies Technical Support

Insulin Receptor Antibody (YA340) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Insulin Receptor.

For research use only. We do not sell to patients.

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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Documentation

Description

Insulin Receptor Antibody (YA340) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Insulin Receptor.
Host

Rabbit
Clonality

Recombinant, Monoclonal
Molecular Weight
Predicted band size: 144 kDa;
Observed band size: 80 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human, Mouse
SwissProt ID
Gene ID
Immunogen

Synthetic peptide corresponding to Human Insulin Receptor R.AA range:12-61.
Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:500
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:50-1:200
Sensitivity Endogenous Purity Protein A affinity purified.
Conjugation Non-conjugated Modification Unmodified
Isotype IgG  
Appearance

Liquid
Formulation

Supplied in 1*TBS (pH7.4), 0.05% BSA and 40% Glycerol. Preservative: 0.05% Sodium Azide.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Background
Function：Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB
Subcellular Localization：Membrane; Single-pass type I membrane protein
Subunit：Probable tetramer of 2 alpha and 2 beta chains linked by disulfide bonds. The alpha chains contribute to the formation of the ligand-binding domain, while the beta chains carry the kinase domain
Database

Entrez Gene: 3643 Human ; 16337 Mouse ;

SwissProt: P06213 Human ; P15208 Mouse ; P15127 Rat

OMIM: 262190 Human

Research Field

Signal Transduction

Documentation
User Guide for Antibodies (1077 KB)

Insulin Receptor Antibody (YA340) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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