2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. 12-OAHSA

12-OAHSA is a component of olive oil. 12-OAHSA has oral activity, and improves glucose homeostasis in insulin resistant obese mice.

For research use only. We do not sell to patients.

12-OAHSA Chemical Structure

12-OAHSA Chemical Structure

CAS No. : 101901-73-9

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Other Forms of 12-OAHSA:

12-OAHSA Related Antibodies

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Description

12-OAHSA is a component of olive oil. 12-OAHSA has oral activity, and improves glucose homeostasis in insulin resistant obese mice[1].

In Vitro

12-OAHSA (25 μM, 24 h) inhibits LPS-induced IL-1b, IL-6, Nos2, and Tnf-α in Raw 264.7 macrophages[1].
12-OAHSA (25 μM, 6 h) reduces IKKβ phosphorylation and increases phosphorylation of p65 in Raw 264.7 macrophages[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

12-OAHSA Related Antibodies
In Vivo

12-OAHSA (30 mg/kg, p.o., for 10 d) inhibits obesity-induced insulin resistance in HFD induced obese C57BL/6 mice[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 10-week HFD induced obese C57BL/6 mice[1]
Dosage: 30 mg/kg
Administration: p.o., for 10 d
Result: Decreased adipose tissue macrophage (ATMs), and CD4+ and CD8+ T lymphocytes in eWAT.
Inhibits obesity-induced adipose tissue inflammation.
Molecular Weight

564.92

Formula

C36H68O4
CAS No.
SMILES

CCCCCCCC/C=C\CCCCCCCC(OC(CCCCCC)CCCCCCCCCCC(O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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12-OAHSA Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

12-OAHSA101901-73-9Endogenous Metaboliteobese miceglucoseinsulinInhibitorinhibitorinhibit

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