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Cat. No.: HY-113878

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12-OAHSA

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12-OAHSA is a component of olive oil. 12-OAHSA has oral activity, and improves glucose homeostasis in insulin resistant obese mice.

For research use only. We do not sell to patients.

Purity: 99.0%
CAS No.: 101901-73-9
Formula: C₃₆H₆₈O₄
Molecular Weight:564.92

Storage:

Solution, -20°C, 2 years

12-OAHSA Chemical Structure

CAS No.: 101901-73-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

12-OAHSA is a component of olive oil. 12-OAHSA has oral activity, and improves glucose homeostasis in insulin resistant obese mice^[1].

All Endogenous Metabolite Isoforms :

In Vitro

12-OAHSA (25 μM, 24 h) inhibits LPS-induced IL-1b, IL-6, Nos2, and Tnf-α in Raw 264.7 macrophages^[1].
12-OAHSA (25 μM, 6 h) reduces IKKβ phosphorylation and increases phosphorylation of p65 in Raw 264.7 macrophages^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

12-OAHSA (30 mg/kg, p.o., for 10 d) inhibits obesity-induced insulin resistance in HFD induced obese C57BL/6 mice^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

10-week HFD induced obese C57BL/6 mice^[1]
Dosage:

30 mg/kg
Administration:

p.o., for 10 d
Result:

Decreased adipose tissue macrophage (ATMs), and CD4+ and CD8+ T lymphocytes in eWAT.
Inhibits obesity-induced adipose tissue inflammation.

Chemical Information

CAS No. 101901-73-9
Appearance Liquid
Molecular Weight 564.92
Formula C₃₆H₆₈O₄
Color Colorless to light yellow
SMILES

CCCCCCCC/C=C\CCCCCCCC(OC(CCCCCC)CCCCCCCCCCC(O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Solution, -20°C, 2 years

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (261 KB)
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Moyo KM, et al. 12-OAHSA is a component of olive oil and mitigates obesity-induced inflammation. J Nutr Biochem. 2022 Dec;110:109127. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- In Vitro
- In Vivo
Chemical Information
Purity & Documentation
References

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12-OAHSA

All Endogenous Metabolite Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

12-OAHSA Related Classifications

HY-113878 Related Classifications