BIM5078
Based on 1 Customer Validation
BIM5078 is a hepatocyte nuclear factor 4α (HNF4α) antagonist that can inhibit the expression of known HNF4α target genes. BIM5078 represses insulin promoter activity through HNF4α antagonism. BIM5078 can be used for the research of cancer and diabetes.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté : 99.90%
- CAS No.: 337506-43-1
- Formule: C14H10ClN3O4S
- Masse moléculaire:351.76
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Stockage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
Voir tous les produits spécifiques à Isoform Nuclear Hormone Receptor 4A/NR4A
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Activité biologique
Description
IC50 & Target
hepatocyte nuclear factor 4α (HNF4α)[1]
In Vitro
BIM5078 (0.63-5μM; 48 h) inhibits the expression of endogenous insulin in T6PNE cells with IC50 value of 930 nM[1].
BIM5078 (2.5-10 μM; 5-48 h) inhibits HNF4α gene expression in HepG2 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 337506-43-1
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Appearance Solid
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Masse moléculaire 351.76
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Formule C14H10ClN3O4S
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Color White to off-white
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SMILES
[O-][N+](C1=CC=C(C(S(=O)(N2C3=C(N=C2C)C=CC=C3)=O)=C1)Cl)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Pureté et documentation
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Fiche technique (277 KB)
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SDS (480 KB)
- English - EN (480 KB)
- Français - FR (480 KB)
- Deutsch - DE (480 KB)
- Norwegian - NO (480 KB)
- Español - ES (480 KB)
- Swedish - SV (480 KB)
- Italian - IT (480 KB)
- Korean - KR (480 KB)
- Portuguese - PT (480 KB)
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Instruction de manipulation (2659 KB)
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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