337506-43-1
337506-43-1
Chemical Structure
BIM5078
- CAS No.: 337506-43-1
- Formula:C14H10ClN3O4S
- Molecular Weight:351.76
IUPAC Name: 1-((2-chloro-5-nitrophenyl)sulfonyl)-2-methyl-1H-benzo[d]imidazole
InChIKey: DLUVMRPVZILBOE-UHFFFAOYSA-N
SMILES: [O-][N+](C1=CC=C(C(S(=O)(N2C3=C(N=C2C)C=CC=C3)=O)=C1)Cl)=O
Biological Activity: BIM5078 is a hepatocyte nuclear factor 4α (HNF4α) antagonist that can inhibit the expression of known HNF4α target genes. BIM5078 represses insulin promoter activity through HNF4α antagonism. BIM5078 can be used for the research of cancer and diabetes[1].
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BIM5078 | BIM5078 is a hepatocyte nuclear factor 4α (HNF4α) antagonist that can inhibit the expression of known HNF4α target genes. BIM5078 represses insulin promoter activity through HNF4α antagonism. BIM5078 can be used for the research of cancer and diabetes. | |||||||||||||||||||||
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References
Keywords
