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Cat. No.: HY-Y1892

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Lauroyl PEG-32 glycerides

Name: Lauroyl PEG-32 glycerides
Brand: MedChemExpress
SKU: HY-Y1892
Price: 50.00 USD
Availability: InStock
Rating: 5 (1 reviews)

1 Cited Publications

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Based on 1 publication(s) in Google Scholar

Lauroyl PEG-32 glycerides is a potential and safe absorption enhancer for improving the absorption of poorly absorbable agents including insulin and calcitonin by pulmonary delivery.

For research use only. We do not sell to patients.

Purity : 96.3%
CAS No.: 121548-04-7

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Lauroyl PEG-32 glycerides Chemical Structure

CAS No.: 121548-04-7

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vivo
Chemical Information
Publications (1)
Solvent & Solubility
- In Vitro
Protocols (1)
Purity & Documentation
References
Calculators
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Biological Activity

Description

Lauroyl PEG-32 glycerides is a potential and safe absorption enhancer for improving the absorption of poorly absorbable agents including insulin and calcitonin by pulmonary delivery.

In Vivo

Lauroyl PEG-32 glycerides is a potential and safe absorption enhancer for improving the absorption of poorly absorbable drugs including insulin and calcitonin by pulmonary delivery. It is found that pulmonary absorptions of FD4, FD10 and FD70 are enhanced in different degree by Lauroyl PEG-32 glycerides in a concentration-dependent manner, and the maximal absorption-enhancing effect is obtained when the concentration of Lauroyl PEG-32 glycerides reaches to 2.0% (w/v). It is also found that the absorption enhancing ability of Lauroyl PEG-32 glycerides is correlated with the molecular weight of model drugs, and the highest absorption enhancement ratio of Lauroyl PEG-32 glycerides is observed when the molecular weight of model drugs reaches to nearly 10000 Da^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 121548-04-7
Appearance Oil
Color Off-white to light yellow
SMILES

[Lauroyl PEG-32 glycerides]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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Pharmaceuticals (Basel)

Optimizing Paclitaxel Oral Absorption and Bioavailability: TPGS Co-Coating via Supercritical Anti-Solvent Fluidized Bed Technology. [Abstract]

2024 Mar 25;17(4):412. PMID: 38675374

Solvent & Solubility

In Vitro:

Ethanol : 100 mg/mL (Need ultrasonic)

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Working solution concentration: 0.22 mg/mL

Protocols

All Signal Pathway Related

Research Protocol for Endocrine Diseases
Endocrine diseases often arise from disrupted hormone production, hormone signaling, or target-tissue responsiveness; for diabetes-focused endocrine disease models, insulin signaling regulates glucose uptake, hepatic glucose output, lipid metabolism, and β-cell compensation. Type 2 diabetes develops through interacting defects in insulin resistance, β-cell dysfunction, adipose inflammation, hepatic glucose overproduction, altered incretin signaling, and ectopic lipid metabolism. A major unresolved question is whether endocrine dysfunction is driven primarily by target-tissue insulin resistance, intrinsic β-cell failure, immune/inflammatory stress, or combined multi-organ failure that differs by disease stage.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zhang H, et al. Improvement of pulmonary absorptions of poorly absorbable drugs using Gelucire 44/14 as an absorption enhancer. J Pharm Pharmacol. 2014 Oct;66(10):1410-20. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

Lauroyl PEG-32 glycerides

1 Cited Publications

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Biological Activity
- Description
- In Vivo
Chemical Information
Publications (1)
Solvent & Solubility
- In Vitro
Protocols
Purity & Documentation
References

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Lauroyl PEG-32 glycerides

Publications Citing Use of MedChemExpress (MCE) Lauroyl PEG-32 glycerides