GPR41 agonist-1
Based on 2 publication(s) in Google Scholar
GPR41 agonist-1 (compound 9) is a potent GPR41 agonist. GPR41 agonist-1 can be used for researching insulin-related disorders.
For research use only. We do not sell to patients.
- Purity: 98.04%
- CAS No.: 506417-09-0
- Formula: C24H23N3O4
- Molecular Weight:417.46
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Publications Citing Use of MedChemExpress (MCE) GPR41 agonist-1
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Biological Activity
GPR41[1]
Chemical Information
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CAS No. 506417-09-0
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Appearance Solid
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Molecular Weight 417.46
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Formula C24H23N3O4
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Color Light yellow to yellow
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SMILES
O=C(C1=C(C)NC2=C(C1C3=CC([N+]([O-])=O)=CC=C3)C(CCC2)=O)NC4=C(C)C=CC=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (2)
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Journal Impact Factor
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Most Recent
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Pharmacol Res
G protein coupled receptor 41 regulates fibroblast activation in pulmonary fibrosis via Gαi/o and downstream Smad2/3 and ERK1/2 phosphorylation. [Abstract]2023 May:191:106754. PMID: 37019194 -
ACS Chem Neurosci
Aberrant Reduction of Short-Chain Fatty Acid (SCFA) Receptor GPR41 and Transporter MCT4 in Prion-Infected Rodent and Cell Models. [Abstract]2025 May 21;16(10):1951-1964. PMID: 40340312
Solvent & Solubility
DMSO : 10 mg/mL (23.95 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3954 mL | 11.9772 mL | 23.9544 mL | 59.8860 mL |
| 5 mM | 0.4791 mL | 2.3954 mL | 4.7909 mL | 11.9772 mL | |
| 10 mM | 0.2395 mL | 1.1977 mL | 2.3954 mL | 5.9886 mL | |
| 15 mM | 0.1597 mL | 0.7985 mL | 1.5970 mL | 3.9924 mL | |
| 20 mM | 0.1198 mL | 0.5989 mL | 1.1977 mL | 2.9943 mL |