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  2. Orphan GPCR SP9155 agonist P550 (mouse, rat)

Orphan GPCR SP9155 agonist P550 (mouse, rat) (Synonyms: 26RFa (mouse, rat))

Cat. No.: HY-P2472
Handling Instructions

Orphan GPCR SP9155 agonist P550 (mouse, rat) (26RFa (mouse, rat)), a member of the RFamide peptide family with orexigenic effect, is the cognate ligand of the mouse orphan receptor GPR103, also designated SP9155 or AQ27.

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Orphan GPCR SP9155 agonist P550 (mouse, rat) Chemical Structure

Orphan GPCR SP9155 agonist P550 (mouse, rat) Chemical Structure

CAS No. : 600171-70-8

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Description

Orphan GPCR SP9155 agonist P550 (mouse, rat) (26RFa (mouse, rat)), a member of the RFamide peptide family with orexigenic effect, is the cognate ligand of the mouse orphan receptor GPR103, also designated SP9155 or AQ27[1][2].

In Vitro

26RFa is a key neuropeptide in the regulation of energy metabolism[2].

In Vivo

26RFa dose-dependently reduces glucose-induced insulin release, inhibits the insulin responses to both arginine and exendin-4 and did not affect glucagon output in rat pancreas[3].

Molecular Weight

2820.17

Formula

C₁₂₆H₁₉₅N₃₇O₃₇

CAS No.

600171-70-8

Sequence Shortening

ASGPLGTLAEELSSYSRRKGGFSFRF-NH2

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Orphan GPCR SP9155 agonist P550 (mouse, rat)26RFa (mouse, rat)Othersorexigenicobesestatusinsulinglucose neuropeptideenergymetabolismInhibitorinhibitorinhibit

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Orphan GPCR SP9155 agonist P550 (mouse, rat)
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