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GLP-1(7-36), amide acetate

(Synonyms: Glucagon-like peptide-1 (GLP-1)(7-36), amide acetate; Human GLP-1 (7-36), amide acetate)
10 Cited Publications
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Based on 10 publication(s) in Google Scholar

GLP-1(7-36), amide acetate is a major intestinal hormone that stimulates glucose-induced insulin secretion from β cells.

For research use only. We do not sell to patients.

  • Purity: 99.01%
  • CAS No.: 1119517-19-9
  • Formula: C149H226N40O45.xC2H4O2
  • Molecular Weight:3297.64 (free base)
  • Storage:

    Sealed storage, away from moisture and light.

    Powder   -80°C, 2 years , -20°C, 1 year

    * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

  • GLP-1(7-36), amide acetate Chemical Structure
    GLP-1(7-36), amide acetate Chemical Structure
  • Experimental Validation Results for GLP-1(7-36), amide acetate
  • Experimental Validation Results for GLP-1(7-36), amide acetate
  • Experimental Validation Results for GLP-1(7-36), amide acetate
  • Experimental Validation Results for GLP-1(7-36), amide acetate
  • Experimental Validation Results for GLP-1(7-36), amide acetate
  • Experimental Validation Results for GLP-1(7-36), amide acetate
CAS No.: 1119517-19-9
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Bio/Physico-chemical AssayCell Proliferation/Viability AssayFlow CytometryWB
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  • Bio/Physico-chemical Assay
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  • Cell Proliferation/Viability Assay
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  • GLP-1(7-36), amide acetate Chemical Structure
    GLP-1(7-36), amide acetate Chemical Structure
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    GLP-1(7-36), amide acetate purchased from MedChemExpress. Usage Cited in: J Pharm Anal. 2024 Aug;14(8):100968. [Abstract]

    Customer Validation
     GLP-1(7-36), amide acetate, as GLP-1 analogues, facilitated Ca2+ mobilization in a dose-dependent manner in GLP-1R-HEK293 cells.

  • 1/16

    GLP-1(7-36), amide acetate purchased from MedChemExpress. Usage Cited in: MAbs. 2021 Jan-Dec;13(1):1893425. [Abstract]

    Customer Validation
     TB-59-2 is a potent agonist in the cAMP assay with a similar EC50 as the GLP-1(7-36), amide acetate (30 min) peptide.

  • 1/16

    GLP-1(7-36), amide acetate purchased from MedChemExpress. Usage Cited in: MAbs. 2021 Jan-Dec;13(1):1893425. [Abstract]

    Customer Validation
     TB01-3 competed with GLP-1(7-36), amide acetate peptide for binding and inhibited the activities of TB01-3 binding in the absence and presence of GLP-1(7-36), amide acetate.

  • 1/16

    GLP-1(7-36), amide acetate purchased from MedChemExpress. Usage Cited in: Int J Endocrinol. 2020 Jun 19;2020:1484321. [Abstract]

    Customer Validation
     GCs were isolated from the ovaries of PCOS model mice (day 54 of life) and treated with increasing doses of GLP-1(7-36), amide acetate (10, 100, and 1000 nM; 24-120 h). Cell viability was measured by CCK-8 assay. The results showed that 100 nM GLP-1(7-36), amide acetate significantly enhanced the viability of MGCs compared with the blank control group.

  • 1/16

    GLP-1(7-36), amide acetate purchased from MedChemExpress. Usage Cited in: Int J Endocrinol. 2020 Jun 19;2020:1484321. [Abstract]

    Customer Validation
     Flow cytometry Annexin V-FITC/PI double staining was used to detect the apoptotic rate of PCOS MGCs in control group and GLP-1(7-36), amide acetate (10 nM, 100 nM, and 1000 nM) treated for 48 hours. The results showed that different concentrations of GLP-1(7-36), amide acetate inhibited the apoptosis of PCOS-associated MGCs treated by DHEA. After being treated for 48 hours, the percentage of apoptotic and late-apoptotic cells was 11.97%, 0.343%, 0.152%, and 1.162%, corresponding to the concentration of GLP-1(7-36), amide acetate of 0, 10, 100, and 1000 nM.

  • 1/16

    GLP-1(7-36), amide acetate purchased from MedChemExpress. Usage Cited in: Int J Endocrinol. 2020 Jun 19;2020:1484321. [Abstract]

    Customer Validation
     Bcl-2, bax, and beta-actin were detected using their specific antibodies by the Western blot analysis for the PCOS MGCs with or without 100 nM GLP-1(7-36), amide acetate interference for 48 hours. The results showed that the expression of bcl-2 protein increased significantly after GLP-1(7-36), amide acetate intervention, while the expression of Bax decreased.

  • GLP-1(7-36), amide acetate