1. Metabolic Enzyme/Protease
    PI3K/Akt/mTOR
    Anti-infection
  2. Glucosidase
    PI3K
    Bacterial
    Antibiotic
  3. 1-Deoxynojirimycin hydrochloride

1-Deoxynojirimycin hydrochloride (Synonyms: Duvoglustat hydrochloride)

Cat. No.: HY-14860A
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1-Deoxynojirimycin hydrochloride (Duvoglustat hydrochloride) is a potent and orally active α-glucosidase inhibitor. 1-Deoxynojirimycin hydrochloride suppresses postprandial blood glucose and is widely used for diabetes mellitus. 1-Deoxynojirimycin hydrochloride possesses antihyperglycemic, anti-obesity, and antiviral features.

For research use only. We do not sell to patients.

1-Deoxynojirimycin hydrochloride Chemical Structure

1-Deoxynojirimycin hydrochloride Chemical Structure

CAS No. : 73285-50-4

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Description

1-Deoxynojirimycin hydrochloride (Duvoglustat hydrochloride) is a potent and orally active α-glucosidase inhibitor. 1-Deoxynojirimycin hydrochloride suppresses postprandial blood glucose and is widely used for diabetes mellitus. 1-Deoxynojirimycin hydrochloride possesses antihyperglycemic, anti-obesity, and antiviral features[1][2].

In Vivo

1-Deoxynojirimycin hydrochloride (Duvoglustat hydrochloride) (20-80 mg/kg; i.v.; daily for four weeks) shows anti-obesity effect [3].
1-Deoxynojirimycin hydrochloride significantly improves insulin sensitivity via activating insulin signaling PI3K/AKT pathway in skeletal muscle of db/db mice[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: db/db mice[3]
Dosage: 20, 40, 80 mg/kg
Administration: Intravenously; daily for four weeks
Result: Significantly reduced body weight, blood glucose and serum insulin levels; Improved glucose tolerance and insulin tolerance.
Clinical Trial
Molecular Weight

199.63

Formula

C₆H₁₄ClNO₄

CAS No.

73285-50-4

SMILES
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Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

1-DeoxynojirimycinDuvoglustatGlucosidasePI3KBacterialAntibioticPhosphoinositide 3-kinasepostprandialbloodglucosediabetesantihyperglycemicanti-obesityantiviralinsulinInhibitorinhibitorinhibit

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Product Name:
1-Deoxynojirimycin hydrochloride
Cat. No.:
HY-14860A
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