1. GPCR/G Protein
    Neuronal Signaling
  2. Somatostatin Receptor
  3. Angiopeptin

Angiopeptin 

Cat. No.: HY-P2090
Handling Instructions

Angiopeptin, a cyclic octapeptide analogue of somatostatin, markedly inhibits myointimal proliferation in response to endothelial cell injury. Angiopeptin is a potent and full agonists to inhibit adenylate cyclase or stimulate extracellular acidification through the sst2 or sst5 receptor. Angiopeptin is a potent inhibitor of growth hormone release and insulin-like growth factor-1 production.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Angiopeptin Chemical Structure

Angiopeptin Chemical Structure

CAS No. : 113294-82-9

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Description

Angiopeptin, a cyclic octapeptide analogue of somatostatin, markedly inhibits myointimal proliferation in response to endothelial cell injury. Angiopeptin is a potent and full agonists to inhibit adenylate cyclase or stimulate extracellular acidification through the sst2 or sst5 receptor. Angiopeptin is a potent inhibitor of growth hormone release and insulin-like growth factor-1 production[1][2].

In Vivo

Angiopeptin (20 and 50μg/kg; i.h.) significantly inhibits neointimal formation[1].
Angiopeptin (20 μg/kg; per day) significantly inhibits coronary artery myointimal proliferation in cardiac allografts by appmximalely 50%[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Rat (model of myointimal proliferation)[1]
Dosage: 20 and 50 μg/kg
Administration: I.h.
Result: Inhibited neointimal formation.
Animal Model: New Zealand white rabbit (model of myointimal proliferation)[1]
Dosage: 20 μg/kg
Administration: Per day
Result: Inhibited coronary artery myointimal proliferation in cardiac allografts by appmximalely 50%.
Molecular Weight

1098.34

Formula

C₅₄H₇₁N₁₁O₁₀S₂

CAS No.
Sequence Shortening

{Nal}CYWKVCT-NH2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Angiopeptin
Cat. No.:
HY-P2090
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