2. GPCR/G Protein Neuronal Signaling
  3. CGRP Receptor
  4. PHM-27 (human)

PHM-27 (human) is a human prepro-vasoactive intestinal polypeptide (27 amino acid). PHM-27 (human) is a potent the human calcitonin receptor agonist with an EC50 of 11 nM. PHM-27 (human) efficiently enhances glucose-induced insulin secretion from beta cells by an autocrine mechanism.

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PHM-27 (human) Chemical Structure

PHM-27 (human) Chemical Structure

CAS No. : 87403-73-4

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PHM-27 (human) Related Antibodies

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Description

PHM-27 (human) is a human prepro-vasoactive intestinal polypeptide (27 amino acid). PHM-27 (human) is a potent the human calcitonin receptor agonist with an EC50 of 11 nM. PHM-27 (human) efficiently enhances glucose-induced insulin secretion from beta cells by an autocrine mechanism[1][2][3].

IC50 & Target

EC50: 11 nM (human calcitonin receptor)[2]
Molecular Weight

2985.41

Formula

C135H214N34O40S
CAS No.
Sequence

{His}{Ala}{Asp}{Gly}{Val}{Phe}{Thr}{Ser}{Asp}{Phe}{Ser}{Lys}{Leu}{Leu}{Gly}{Gln}{Leu}{Ser}{Ala}{Lys}{Lys}{Tyr}{Leu}{Glu}{Ser}{Leu}{Met}-NH2
Sequence Shortening

HADGVFTSDFSKLLGQLSAKKYLESLM-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PHM-27 (human) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PHM-27 (human)87403-73-4CGRP ReceptorCalcitonin gene-related peptide receptorCalcitonindiabetespreprovasoactiveintestinalpolypeptideglucoseautocrineInhibitorinhibitorinhibit

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