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Cat. No.: HY-P3577

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[Tyr0] Gastric Inhibitory Peptide (23-42), human

[Tyr0] Gastric Inhibitory Peptide (23-42), human, a glucose-dependent insulinotropic polypeptide (GIP), is a weak inhibitor of gastric acid secretion that also stimulates insulin secretion. [Tyr0] Gastric Inhibitory Peptide (23-42), human can be used in diabetes, obesity research.

For research use only. We do not sell to patients.

CAS No.: 121765-67-1
Formula: C₁₁₉H₁₈₂N₃₄O₃₁
Molecular Weight:2584.93

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

[Tyr0] Gastric Inhibitory Peptide (23-42), human Chemical Structure

CAS No.: 121765-67-1

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vivo
Chemical Information
Purity & Documentation
References
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Biological Activity

Description

In Vivo

GIPR^-/- mice have higher blood glucose levels and impaired initial insulin response after oral glucose loading. In GIPR^+/+ mice, a high-fat diet did not increase postprandial intake blood glucose levels, whereas it significantly increased in GIPR^-/- mice^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 121765-67-1
Molecular Weight 2584.93
Formula C₁₁₉H₁₈₂N₃₄O₃₁
Sequence Shortening

YVNWLLAQKGKKNDWKHNITQ
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (259 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. LaPelusa A, et al. Biochemistry, Bombesin[M]//StatPearls [Internet]. StatPearls Publishing, 2021.

[2]. K Miyawaki, et al. Glucose intolerance caused by a defect in the entero-insular axis: a study in gastric inhibitory polypeptide receptor knockout mice. Proc Natl Acad Sci U S A. 1999 Dec 21;96(26):14843-7. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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[Tyr0] Gastric Inhibitory Peptide (23-42), human

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[Tyr0] Gastric Inhibitory Peptide (23-42), human

Biological Activity

Description

In Vivo

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

[Tyr0] Gastric Inhibitory Peptide (23-42), human Related Classifications

HY-P3577 Related Classifications

Bioz

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