1. Recombinant Proteins

Recombinant protein is a protein encoded by a recombinant DNA that has been cloned in a system that supports expression of the gene and translation of mRNA. The host cells used for recombinant protein production can be bacteria, yeast, insect cell, and mammalian cell.

MedChemExpress (MCE) offers a comprehensive collection of recombinant proteins with excellent lot-to-lot consistency, superior activity and low endotoxin level. MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.

Superior Bioactivity

Validated by relevant in vitro or in vivo assays

Broad Categories

Including cytokines, receptors, enzymes, etc.

High Purity

Greater than 95%

Custom Protein Service

One-stop service from gene to protein


  • MedChemExpress (MCE) provides a range of cytokines and growth factors, including interleukins, chemokines, interferons, transforming growth factors, fibroblast growth factors, as well as the cytokine receptor family.

  • Covering a series of immune checkpoint molecules, including PD-1/PD-L1, CTLA-4, TIM-3, OX40, TIGIT, and novel immune checkpoint proteins such as butyrophilins (BTNs).

  • Covering popular targets, including BCMA, CD19, MSLN, HER2, MUC1, CD22, ROR1, and providing labeled target antigens, such as fluorescently labeled and biotin-labeled, to support CAR-T research and development.

  • CD molecules function as cell adhesion molecules, cytokine receptors, ion channels, or nutrient transport proteins, playing various roles in immune system function. CD molecules are commonly used as cell markers for immune antigen recognition.

  • The binding activity between the Fc fragment of antibodies and receptors affects the efficacy of antibody drugs. MedChemExpress (MCE) offers a range of high-quality recombinant Fc receptor proteins for antibody drug modification and evaluation, facilitating the development of antibody drugs.

  • Receptor proteins include enzyme-linked receptors, cell adhesion molecules, G protein-coupled receptors, nuclear receptors, pattern recognition receptors, Notch, and other receptor families.

  • Most biological processes in organisms are regulated by enzymes. MedChemExpress (MCE) provides a variety of enzyme-related proteins, including various families of enzymes and inhibitors, such as MMPs, proteases, CDKs, phosphatases, protease inhibitors, kinase inhibitors, and CDK inhibitors.

  • MedChemExpress (MCE) has developed a series of high-quality recombinant proteins, including C3, C5, MASP, complement regulatory factors, etc., to support research on the complement system mechanism and related diseases.

  • Ubiquitination regulates various cellular processes, including cell division and differentiation, responses to environmental stress, cell differentiation, immune reactions, DNA repair, and apoptosis.

  • MedChemExpress (MCE) provides a variety of recombinant viral proteins, including influenza viruses, coronaviruses, HIV, hepatitis viruses, and more, to support research on viral infections.

  • MedChemExpress (MCE) has developed nearly a thousand recombinant biotinylated and Avi-Tag proteins, which can be used in protein purification, protein-protein interactions, detection, screening, and other research applications.

  • Fluorescent labeling is a versatile tool for studying molecular interactions, tracking protein movement, and probing protein biological functions.

  • MedChemExpress (MCE) GMP recombinant proteins are manufactured under specific guidelines to ensure product quality and consistency. Each lot of our GMP-grade recombinant proteins undergoes rigorous QC testing tests.

  • Animal-free recombinant proteins have the same biological activity as proteins produced using standard laboratory techniques, while researchers do not have to worry at all about traces of animal components or mammalian pathogens affecting their experiments.

  • MedChemExpress (MCE) provides key proteins in signaling pathways, transporters, or popular drug target proteins such as Wnt3a, Fibronectin, CLDN6, APOE2, etc.

Hot Topics
An organoid is a 3D multicellular in vitro tissue construct that mimics the complex structure and functionality of corresponding in vivo organ. MedChemExpress (MCE) provides a range of cytokines, small molecule inhibitors, basement membrane matrix, and various organoid culture kits.

Immune Checkpoint Proteins

ICPs have been identified and studied in cancer, including PD-1, CTLA-4, LAG3 and TIGIT, etc. MedChemExpress (MCE) offers recombinant proteins, specific small molecule inhibitors/agonists, and antibody inhibitors for immune checkpoint research.


SARS-CoV is a positive-stranded RNA virus belonging to the family Coronaviridae. The SARS-COV-2 genome encodes at least sixteen non-structural proteins and four structural proteins.

Stem Cell Related Research

Stem cells are able to differentiate into different types of cells in the body and have unique abilities to self-renew and recreate functional tissues. MedChemExpress (MCE) offers a range of products related to stem cell culture.

Broad Categories
Cytokines, Growth Factors, Receptor Proteins, Enzymes & Regulators, Viral Proteins, etc.
Different Species
Human, Mouse, Rat, Monkey, Pig, Rabbit, Virus, etc.
Low Endotoxin Levels
Measured by LAL assay
High Purity
Tested by SDS-PAGE & HPLC
Superior Biological Activity
Validated by relevant in vitro or in vivo assays
Excellent Lot-to-Lot Consistency
Confirmed by Lot-to-Lot data
Full Range Sizes
Different pre-packaged sizes for various needs
Competitive Price
High quality with a reasonable price
High Purity
The purity of mouse IL-13R alpha 2 is greater than 95% as analyzed by SDS-PAGE under reducing (R) condition and HPLC.
Superior Biological Activity
Human GM-CSF stimulates cell proliferation of TF-1 cells with an ED50 of less than 0.5 ng/mL.
Excellent Lot-to-Lot Consistency
The ED50 of MedChemExpress (MCE) human VEGF165 from three different lots are similar.
Activity Comparison
The ED50 of human VEGF165 from MedChemExpress (MCE)’s each Lot is lower than of Competitor P.
Recombinant Protein Expression Service
One-stop service from gene design to protein preparation
Independently developed high expression vectors and strains
Professional R & D team of recombinant protein technology
Providing customized services of high-purity protein from mg to g
Large-scale protein production platform
01 Codon
02 Gene
03 Construction of
Expression Vector
04 Strain
05 Protein
06 Purification
& QC
07 Protein