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  3. ITK antagonist

ITK antagonist 

Cat. No.: HY-13232
Handling Instructions

ITK antagonist (compound 10 n) is a potent, orally active and selective ITK (Interleukin-2 inducible T-cell kinase) antagonist (IC50=1 and 20 nM in different assays). ITK antagonist inhibits insulin receptor kinase (IRK) with an IC50 of 160 nM.

For research use only. We do not sell to patients.

ITK antagonist Chemical Structure

ITK antagonist Chemical Structure

CAS No. : 1149753-56-9

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Description

ITK antagonist (compound 10 n) is a potent, orally active and selective ITK (Interleukin-2 inducible T-cell kinase) antagonist (IC50=1 and 20 nM in different assays). ITK antagonist inhibits insulin receptor kinase (IRK) with an IC50 of 160 nM[1].

In Vitro

ITK antagonist inhibits DT40 cell (IC50=4 nM) and shows IL-2 inhibition (IC50=20 nM)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

494.65

Formula

C26H34N6O2S

CAS No.
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
ITK antagonist
Cat. No.:
HY-13232
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