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Steroids

A steroid is an organic compound with four rings arranged in a specific molecular configuration, composed of seventeen carbon atoms, bonded in four "fused" rings: three six-member cyclohexane rings (rings A, B and C in the first illustration) and one five-member cyclopentane ring (the D ring). Hundreds of steroids are found in plants, animals and fungi. Examples include the dietary lipid cholesterol, the sex hormones estradiol and testosterone and the anti-inflammatory drug dexamethasone. Steroids have two principal biological functions: certain steroids (such as cholesterol) are important components of cell membranes which alter membrane fluidity, and many steroids are signaling molecules which activate steroid hormone receptors.

Steroids (213):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N0583
    Hydrocortisone 50-23-7 99.90%
    Hydrocortisone (Cortisol) is a steroid hormone or glucocorticoid secreted by the adrenal cortex.
    Hydrocortisone
  • HY-B0141
    Estradiol 50-28-2 99.99%
    Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway.
    Estradiol
  • HY-N0437
    Progesterone 57-83-0 99.66%
    Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.
    Progesterone
  • HY-17024
    Cyclopamine 4449-51-8 ≥98.0%
    Cyclopamine is a Hedgehog (Hh) pathway antagonist with an IC50 of 46 nM in the Hh cell assay. Cyclopamine is also a selective Smo inhibitor.
    Cyclopamine
  • HY-B1618
    Corticosterone 50-22-6
    Corticosterone is an adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid.
    Corticosterone
  • HY-113134
    25-Hydroxycholesterol 2140-46-7 ≥98.0%
    25-Hydroxycholesterol is a metabolite of cholesterol that is produced and secreted by macrophages in response to Toll-like receptor (TLR) activation. 25-hydroxycholesterol is a potent (EC50≈65 nM) and selective suppressor of IgA production by B cells.
    25-Hydroxycholesterol
  • HY-N0322
    Cholesterol 57-88-5 ≥98.0%
    Cholesterol is the major sterol in mammals and is makes up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins. Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist.
    Cholesterol
  • HY-12033
    2-Methoxyestradiol 362-07-2 99.82%
    2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa.
    2-Methoxyestradiol
  • HY-B0469
    Medroxyprogesterone acetate 71-58-9 99.88%
    Medroxyprogesterone acetate is a widely used synthetic steroid by its interaction with progesterone, androgen and glucocorticoid receptors.
    Medroxyprogesterone acetate
  • HY-13771
    Ursodiol 128-13-2 ≥98.0%
    Ursodiol (Ursodeoxycholic acid; UDCA) is a potent liver-specific fatty acid transport protein 5 (FATP5) inhibitor. Ursodiol inhibit LCFA uptake by primary hepatocytes in a FATP5-dependent manner. Ursodiol reduces cholesterol absorption and is used to dissolve gallstones and has the potential for obesity-associated fatty liver disease research.
    Ursodiol
  • HY-B0214
    Prednisone 53-03-2 99.82%
    Prednisone (Adasone) is a synthetic corticosteroid agent that is particularly effective as an immunosuppressant compound.
    Prednisone
  • HY-B1269
    Testosterone propionate 57-85-2 99.89%
    Testosterone propionate is a slower releasing anabolic steroid used mainly in the treatment of low testosterone levels in men.
    Testosterone propionate
  • HY-B1357
    Digitoxin 71-63-6
    Digitoxin is an effective Na+/K+-ATPase inhibitor, the EC50 value of Digitoxin is 0.78 μM.
    Digitoxin
  • HY-17463
    Prednisolone 50-24-8 99.92%
    Prednisolone is a potent, orally active corticosteroid and a glucocorticoid. Prednisolone possesses about four times the anti-inflammatory activity of hydrocortisone while causing less salt and water retention. Prednisolone can be used for ocular, anti-inflammatory research.
    Prednisolone
  • HY-113313
    Aldosterone 52-39-1 ≥99.0%
    Aldosterone is the primary mineralocorticoid. Aldosterone is a steroid hormone, and it is synthesized and secreted in response to renin-angiotensin system activation (RAS) or high dietary potassium by the zona glomerulosa (ZG) of the adrenal cortex. Aldosterone activity is dependent by the binding and activation of the cytoplasmic/nuclear mineralocorticoid receptor (MR) at cellular level.
    Aldosterone
  • HY-N2065
    Withaferin A 5119-48-2 99.92%
    Withaferin A is a steroidal lactone isolated from Withania somnifera, inhibits NF-kB activation and targets vimentin, with potent antiinflammatory and anticancer activities. Withaferin A is an inhibitor of endothelial protein C receptor (EPCR) shedding.
    Withaferin A
  • HY-N0877
    Bufalin 465-21-4 99.86%
    Bufalin is an active component isolated from Chan Su, acts as a potent Na+/K+-ATPase inhibitor, binds to the subunit α1, α2 and α3, with Kd of 42.5, 45 and 40 nM, respectively. Anti-cancer activity.
    Bufalin
  • HY-N2334
    Glycochenodeoxycholic acid 640-79-9 ≥98.0%
    Glycochenodeoxycholic acid (Chenodeoxycholylglycine) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) induces hepatocyte apoptosis.
    Glycochenodeoxycholic acid
  • HY-W020033
    Lanosterol 79-63-0 ≥98.0%
    Lanosterol is an intermediate of cholesterol synthesis and use of lanosterol induces ubiquitination and degradation of a rate-controlling enzyme of cholesterol synthesis, i.e., HMG CoA reductase. Lanosterol suppresses the aggregation and cytotoxicity of misfolded proteins linked with neurodegenerative diseases.
    Lanosterol
  • HY-B0234
    Estrone 53-16-7
    Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells.
    Estrone