1. Protein Tyrosine Kinase/RTK
  2. IGF-1R
  3. Indirubin Derivative E804

Indirubin Derivative E804 

Cat. No.: HY-18785
Handling Instructions

E 804 is a potent inhibitor of Insulin-like Growth Factor 1 Receptor (IGF1R), with an IC50 of 0.65 μM for IGF1R.

For research use only. We do not sell to patients.

Indirubin Derivative E804 Chemical Structure

Indirubin Derivative E804 Chemical Structure

CAS No. : 854171-35-0

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Description

E 804 is a potent inhibitor of Insulin-like Growth Factor 1 Receptor (IGF1R), with an IC50 of 0.65 μM for IGF1R.

IC50 & Target

IC50: 0.65 μM (IGF1R)[1].

In Vitro

Indirubin Derivative E804 is a water-soluble indirubin derivative as potent inhibitor of Insulin-like Growth Factor 1 Receptor (IGF1R), with an IC50 of 0.65 μM. Indirubin Derivative E804 also inhibits CDK2/CycE with an EC50 of 0.23 μM[1].

Molecular Weight

365.38

Formula

C₂₀H₁₉N₃O₄

CAS No.

854171-35-0

SMILES

O=C1NC2=C(C=CC=C2)/C1=C3NC4=C(C=CC=C4)C/3=N/OCCC(O)CO

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Indirubin Derivative E804
Cat. No.:
HY-18785
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