264218-23-7
264218-23-7
Chemical Structure
SB 415286
- CAS No.: 264218-23-7
- Formula:C16H10ClN3O5
- Molecular Weight:359.72
IUPAC Name: 3-((3-chloro-4-hydroxyphenyl)amino)-4-(2-nitrophenyl)-1H-pyrrole-2,5-dione
InChIKey: PQCXVIPXISBFPN-UHFFFAOYSA-N
SMILES: O=C(C(NC1=CC=C(O)C(Cl)=C1)=C2C3=CC=CC=C3[N+]([O-])=O)NC2=O
Biological Activity: SB 415286 is a potent and selective cell permeable inhibitor of GSK-3α, with an IC50 of 77.5 nM, and a Ki of 30.75 nM; SB 415286 is equally effective at inhibiting human GSK-3α and GSK-3β.
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SB 415286 | 99.46% | SB 415286 is a potent and selective cell permeable inhibitor of GSK-3α, with an IC50 of 77.5 nM, and a Ki of 30.75 nM; SB 415286 is equally effective at inhibiting human GSK-3α and GSK-3β. | ||||||||||||||||||||
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SB 415286 (Standard) | ≥98% | SB 415286 (Standard) is the analytical standard of SB 415286. This product is intended for research and analytical applications. SB 415286 is a potent and selective cell permeable inhibitor of GSK-3α, with an IC50 of 77.5 nM, and a Ki of 30.75 nM; SB 415286 is equally effective at inhibiting human GSK-3α and GSK-3β. | ||||||||||||||||||||
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Keywords
