1. Signaling Pathways
  2. Epigenetics
    TGF-beta/Smad
  3. PKC
  4. PKCη Inhibitors

PKCη Inhibitors

PKC

PKCα

PKCβ

PKCγ

PKCδ

PKCε

PKCη

PKCζ

PKCθ

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform PKCη together.

Please try each isoform separately.

PKCη Specific Inhibitors
Product Name PKCη PKCα PKCβ PKCγ PKCδ PKCε PKCζ PKCθ PKCη Selectivity Purity
Midostaurin
nPKC-η, IC50: 16 nM
cPKC-α, IC50: 22 nM
cPKC-β1, IC50: 30 nM
cPKC-β2, IC50: 31 nM
cPKC-γ, IC50: 24 nM
nPKC-δ, IC50: 33 nM
nPKC-ε, IC50: 1250 nM
aPKC-ζ, IC50: 465000 nM
  Pan Inhibitor 99.89%
Sotrastaurin
PKCη, Ki: 1.8 nM
PKCα, Ki: 0.95 nM
PKCβI, Ki: 0.64 nM
 
PKCδ, Ki: 2.1 nM
PKCε, Ki: 3.2 nM
 
PKCθ, Ki: 0.22 nM
Pan Inhibitor 99.83%
Ruboxistaurin hydrochloride
PKCη, IC50: 52 nM
PKCα, IC50: 360 nM
PKCβI, IC50: 4.7 nM
PKCβII, IC50: 5.9 nM
PKCγ, IC50: 300 nM
PKCδ, IC50: 250 nM
PKCε, IC50: 600 nM
    Pan Inhibitor 98.88%
Rottlerin
PKCη, IC50: 82 μM (baculovirus-infected Sf9 insect cells)
PKCα, IC50: 30 μM (baculovirus-infected Sf9 insect cells)
PKCβ, IC50: 42 μM (baculovirus-infected Sf9 insect cells)
PKCγ, IC50: 40 μM (baculovirus-infected Sf9 insect cells)
PKCδ, IC50: 3 μM (Porcine spleen)
PKCε, IC50: 100 μM (baculovirus-infected Sf9 insect cells)
PKCζ, IC50: 100 μM (baculovirus-infected Sf9 insect cells)
  Pan Inhibitor >95.0%