2360523-76-6
2360523-76-6
Chemical Structure
Hu7691
- CAS No.: 2360523-76-6
- Formula:C22H22ClF3N4O
- Molecular Weight:450.88
IUPAC Name: N-((3S,4S)-4-(3,4-difluorophenyl)piperidin-3-yl)-2-fluoro-4-(1-methyl-1H-pyrazol-5-yl)benzamide hydrochloride
InChIKey: WHVFOLXIIVBJTJ-ICCPGPOKSA-N
SMILES: O=C(N[C@@H]1CNCC[C@H]1C2=CC=C(F)C(F)=C2)C3=CC=C(C4=CC=NN4C)C=C3F.[H]Cl
Biological Activity: Hu7691 is an orally active, selective Akt inhibitor with IC50s of 4.0 nM, 97.5 nM, 28 nM for Akt1, Akt2 and Akt3, respectively. Hu7691 inhibits tumor growth and enables decrease of cutaneous toxicity in mice[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Hu7691 | 99.91% | Hu7691 is an orally active, selective Akt inhibitor with IC50s of 4.0 nM, 97.5 nM, 28 nM for Akt1, Akt2 and Akt3, respectively. Hu7691 inhibits tumor growth and enables decrease of cutaneous toxicity in mice. | ||||||||||||||||||||
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References
Keywords
