1. Signaling Pathways
  2. Epigenetics
    TGF-beta/Smad
  3. PKC
  4. PKCδ Inhibitors

PKCδ Inhibitors

PKC

PKCα

PKCβ

PKCγ

PKCδ

PKCε

PKCη

PKCζ

PKCθ

PKCμ

PKCι

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform PKCδ together.

Please try each isoform separately.

PKCδ Specific Inhibitors & Modulators
Product Name PKCδ PKCα PKCβ PKCγ PKCε PKCη PKCζ PKCθ PKCμ PKCδ Selectivity Purity
VTX-27
PKCδ, Ki: 16 nM
PKCα, Ki: 356 nM
         
PKCθ, Ki: 0.08 nM
  Selective Inhibitor 99.64%
Delcasertib
δPKC
                Selective Inhibitor 98.21%
BJE6-106
PKCδ, IC50: 0.05 μM
PKCα, IC50: 50 μM
              Selective Inhibitor 98.17%
PKC-theta inhibitor 1
PKCδ, Ki: 392 μM
PKCα, Ki: 1020 μM
         
PKCθ, Ki: 6 nM
  Selective Inhibitor
Go 6983
PKCδ, IC50: 10 nM
PKCα, IC50: 7 nM
PKCβ, IC50: 7 nM
PKCγ, IC50: 6 nM
   
PKCζ, IC50: 60 nM
 
PKCμ, IC50: 20000 nM
Pan Inhibitor 98.01%
Midostaurin
nPKC-δ, IC50: 33 nM
cPKC-α, IC50: 22 nM
cPKC-β1, IC50: 30 nM
cPKC-β2, IC50: 31 nM
cPKC-γ, IC50: 24 nM
nPKC-ε, IC50: 1250 nM
nPKC-η, IC50: 160 nM
aPKC-ζ, IC50: 465000 nM
    Pan Inhibitor ≥98.0%
Ruboxistaurin
PKCδ, IC50: 250 nM
PKCα, IC50: 360 nM
PKC-βI, IC50: 4.7 nM
PKC-βII, IC50: 5.9 nM
PKCγ, IC50: 300 nM
PKCε, IC50: 600 nM
PKCη, IC50: 52 nM
      Pan Inhibitor 98.03%
Sotrastaurin
PKCδ, Ki: 2.1 nM
PKCα, Ki: 0.95 nM
PKCβI, Ki: 0.64 nM
 
PKCε, Ki: 3.2 nM
PKCη, Ki: 1.8 nM
 
PKCθ, Ki: 0.22 nM
  Pan Inhibitor 99.89%
Rottlerin
PKCδ, IC50: 3 μM (Porcine spleen)
PKCα, IC50: 30 μM (baculovirus-infected Sf9 insect cells)
PKCβ, IC50: 42 μM (baculovirus-infected Sf9 insect cells)
PKCγ, IC50: 40 μM (baculovirus-infected Sf9 insect cells)
PKCε, IC50: 100 μM (baculovirus-infected Sf9 insect cells)
PKCη, IC50: 82 μM (baculovirus-infected Sf9 insect cells)
PKCζ, IC50: 100 μM (baculovirus-infected Sf9 insect cells)
    Pan Inhibitor ≥95.0%
Ingenol Mebutate
PKC-δ, Ki: 0.376 nM
PKC-α, Ki: 0.3 nM
PKC-β, Ki: 0.105 nM
PKC-γ, Ki: 0.162 nM
PKC-ε, Ki: 0.171 nM
        Pan Modulator 99.07%
Ruboxistaurin hydrochloride
PKCδ, IC50: 250 nM
PKCα, IC50: 360 nM
PKCβI, IC50: 4.7 nM
PKCβII, IC50: 5.9 nM
PKCγ, IC50: 300 nM
PKCε, IC50: 600 nM
PKCη, IC50: 52 nM
      Pan Inhibitor 99.84%
Delcasertib hydrochloride
δPKC
                Pan Inhibitor 98.11%
AS2521780
PKCδ, IC50: 160 nM
PKCα, IC50: 160 nM
   
PKCε, IC50: 18 nM
   
PKCθ, IC50: 0.48 nM
  Pan Inhibitor