1. Signaling Pathways
  2. Epigenetics
    TGF-beta/Smad
  3. PKC
  4. PKCβ Inhibitors

PKCβ Inhibitors

PKC

PKCα

PKCβ

PKCγ

PKCδ

PKCε

PKCη

PKCζ

PKCθ

PKCμ

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform PKCβ together.

Please try each isoform separately.

PKCβ Specific Inhibitors & Modulators
Product Name PKCβ PKC PKCα PKCγ PKCδ PKCε PKCη PKCζ PKCθ PKCμ PKCβ Selectivity Purity
Ruboxistaurin hydrochloride
PKCβI, IC50: 4.7 nM
PKCβII, IC50: 5.9 nM
 
PKCα, IC50: 360 nM
PKCγ, IC50: 300 nM
PKCδ, IC50: 250 nM
PKCε, IC50: 600 nM
PKCη, IC50: 52 nM
      Selective Inhibitor 99.84%
PKC β pseudosubstrate
PKC-β
                  Selective Inhibitor
PKC β pseudosubstrate TFA
PKCβ
                  Selective Inhibitor
Midostaurin
cPKC-β1, IC50: 30 nM
cPKC-β2, IC50: 31 nM
 
cPKC-α, IC50: 22 nM
cPKC-γ, IC50: 24 nM
nPKC-δ, IC50: 33 nM
nPKC-ε, IC50: 1250 nM
nPKC-η, IC50: 160 nM
aPKC-ζ, IC50: 465000 nM
    Pan Inhibitor 99.89%
Go 6983
PKCβ, IC50: 7 nM
 
PKCα, IC50: 7 nM
PKCγ, IC50: 6 nM
PKCδ, IC50: 10 nM
   
PKCζ, IC50: 60 nM
 
PKCμ, IC50: 20000 nM
Pan Inhibitor 98.01%
Bisindolylmaleimide I
PKCβII, IC50: 16 nM
PKCβI, IC50: 17 nM
Bovine brain PKC, IC50: 10 nM
PKCα, IC50: 20 nM
PKCγ, IC50: 20 nM
            Pan Inhibitor 98.14%
Sotrastaurin
PKCβI, Ki: 0.64 nM
 
PKCα, Ki: 0.95 nM
 
PKCδ, Ki: 2.1 nM
PKCε, Ki: 3.2 nM
PKCη, Ki: 1.8 nM
 
PKCθ, Ki: 0.22 nM
  Pan Inhibitor 99.83%
Enzastaurin
PKCβ, IC50: 6 nM
 
PKCα, IC50: 39 nM
PKCγ, IC50: 83 nM
 
PKCε, IC50: 110 nM
        Pan Inhibitor 99.90%
Rottlerin
PKCβ, IC50: 42 μM (baculovirus-infected Sf9 insect cells)
 
PKCα, IC50: 30 μM (baculovirus-infected Sf9 insect cells)
PKCγ, IC50: 40 μM (baculovirus-infected Sf9 insect cells)
PKCδ, IC50: 3 μM (Porcine spleen)
PKCε, IC50: 100 μM (baculovirus-infected Sf9 insect cells)
PKCη, IC50: 82 μM (baculovirus-infected Sf9 insect cells)
PKCζ, IC50: 100 μM (baculovirus-infected Sf9 insect cells)
    Pan Inhibitor 96.84%
Ro 31-8220 mesylate
PKC-βI, IC50: 24 nM
PKC-βII, IC50: 14 nM
Rat Brain PKC, IC50: 23 nM
PKC-α, IC50: 5 nM
PKC-γ, IC50: 27 nM
 
PKC-ε, IC50: 24 nM
        Pan Inhibitor 99.28%
Ingenol Mebutate
PKC-β, Ki: 0.105 nM
 
PKC-α, Ki: 0.3 nM
PKC-γ, Ki: 0.162 nM
PKC-δ, Ki: 0.376 nM
PKC-ε, Ki: 0.171 nM
        Pan Modulator 99.07%
Afuresertib
PKC-βI, IC50: 430 nM
         
PKCη, IC50: 210 nM
 
PKCθ, IC50: 510 nM
  Pan Inhibitor 99.23%
Afuresertib hydrochloride
PKC-βI, IC50: 430 nM
         
PKCη, IC50: 210 nM
 
PKCθ, IC50: 510 nM
  Pan Inhibitor 98.02%
PKCβ inhibitor 1
human PKCβ1, IC50: 21 nM
human PKCβ2, IC50: 5 nM
 
PKCα, IC50: 331 nM
              Pan Inhibitor 98.21%
Ro 32-0432 hydrochloride
PKC-βI, IC50: 28 nM
PKC-βII, IC50: 30 nM
 
PKCα, IC50: 9.3 nM
PKCγ, IC50: 36.5 nM
 
PKCε, IC50: 108.3 nM
        Pan Inhibitor
Bisindolylmaleimide VIII acetate
PKC-βI, IC50: 195 nM
PKC-βII, IC50: 163 nM
Rat Brain PKC, IC50: 158 nM
PKC-α, IC50: 53 nM
PKC-γ, IC50: 213 nM
 
PKC-ε, IC50: 175 nM
        Pan Inhibitor