1. Signaling Pathways
  2. Cell Cycle/DNA Damage
    Stem Cell/Wnt
    TGF-beta/Smad
  3. ROCK
  4. ROCK2 Inhibitors

ROCK2 Inhibitors

ROCK

ROCK1

ROCK2

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Sorry. There is currently no product that acts on isoform ROCK2 together.

Please try each isoform separately.

ROCK2 Specific Inhibitors
Product Name ROCK2 ROCK1 ROCK2 Selectivity Purity
Fasudil Hydrochloride
ROCK2, IC50: 0.158 μM
p160ROCK, Ki: 0.33 μM
Selective Inhibitor 99.91%
Chroman 1
ROCK2, IC50: 1 nM
  Selective Inhibitor 99.90%
CMPD101
ROCK2, IC50: 1.4 μM
  Selective Inhibitor
SLx-2119
ROCK2, IC50: 105 nM
ROCK1, IC50: 24 μM
Selective Inhibitor 99.42%
H-1152 dihydrochloride
ROCKII, IC50: 12 nM
  Selective Inhibitor >98.0%
SR-3677
ROCK-II, IC50: 3 nM
ROCK-I, IC50: 56 nM
Selective Inhibitor 99.91%
H-1152
ROCKII, IC50: 12 nM
  Selective Inhibitor
Fasudil
ROCK2, IC50: 0.158 μM
p160ROCK, Ki: 0.33 μM
Selective Inhibitor
ROCK2-IN-2
ROCK2, IC50: 1 μM
  Selective Inhibitor
ROCK-IN-1
ROCK2, IC50: 1.2 nM
  Selective Inhibitor
Y-27632 dihydrochloride
ROCK-II, Ki: 300 nM
ROCK-I, Ki: 220 nM
Pan Inhibitor 99.83%
Y-27632
ROCK-II, Ki: 300 nM
ROCK-I, Ki: 220 nM
Pan Inhibitor 99.73%
Ripasudil
ROCK2, IC50: 19 nM
ROCK1, IC50: 51 nM
Pan Inhibitor 99.75%
GSK269962A
ROCK2, IC50: 4 nM
ROCK1, IC50: 1.6 nM
Pan Inhibitor 98.01%
ROCK-IN-2
ROCK-2, IC50: 1.1 nM
ROCK-1, IC50: 0.6 nM
Pan Inhibitor 99.46%
RKI-1447
ROCK2, IC50: 6.2 nM
ROCK1, IC50: 14.5 nM
Pan Inhibitor 97.26%
AT13148
ROCKII, IC50: 4 nM
ROCKI, IC50: 6 nM
Pan Inhibitor 99.54%
Hydroxyfasudil
ROCK2, IC50: 0.72 μM
ROCK1, IC50: 0.73 μM
Pan Inhibitor 98.11%
BDP5290
ROCK2, IC50: 50 nM
ROCK1, IC50: 5 nM
Pan Inhibitor >98.0%
SAR407899
ROCK-2, IC50: 102 nM
ROCK-1, IC50: 276 nM
Pan Inhibitor 99.97%
SAR407899 hydrochloride
ROCK-2, IC50: 102 nM
ROCK-1, IC50: 276 nM
Pan Inhibitor >98.0%
ROCK inhibitor-2
ROCK2, IC50: 2 nM
ROCK1, IC50: 17 nM
Pan Inhibitor 99.59%
Rho-Kinase-IN-1
ROCK2, Ki: 3.9 nM
ROCK1, Ki: 30.5 nM
Pan Inhibitor 99.72%
Hydroxyfasudil hydrochloride
ROCK2, IC50: 0.72 μM
ROCK1, IC50: 0.73 μM
Pan Inhibitor 99.40%
SB-772077B dihydrochloride
ROCK2, IC50: 6 nM
ROCK1, IC50: 5.6 nM
Pan Inhibitor >99.0%
Ripasudil free base
ROCK2, IC50: 19 nM
ROCK1, IC50: 51 nM
Pan Inhibitor