1. Signaling Pathways
  2. Cell Cycle/DNA Damage
    Cytoskeleton
    Stem Cell/Wnt
    TGF-beta/Smad
  3. ROCK
  4. ROCK2 Inhibitors

ROCK2 Inhibitors

ROCK

ROCK1

ROCK2

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform ROCK2 together.

Please try each isoform separately.

ROCK2 Specific Inhibitors
Product Name ROCK2 ROCK1 ROCK2 Selectivity Purity
Chroman 1
ROCK2, IC50: 1 pM
ROCK1, IC50: 52 pM
Selective Inhibitor 99.90%
Belumosudil
ROCK2, IC50: 105 nM
ROCK1, IC50: 24 μM
Selective Inhibitor 99.77%
H-1152 dihydrochloride
ROCKII, IC50: 12 nM
  Selective Inhibitor ≥98.0%
CMPD101
ROCK2, IC50: 1.4 μM
  Selective Inhibitor ≥98.0%
CRT0066854
ROCK2, IC50: 620 nM
  Selective Inhibitor ≥99.0%
SR-3677
ROCK-II, IC50: 3 nM
ROCK-I, IC50: 56 nM
Selective Inhibitor 99.91%
CRT0066854 hydrochloride
ROCKII, IC50: 620 nM
  Selective Inhibitor
H-1152
ROCKII, IC50: 12 nM
  Selective Inhibitor
Belumosudil mesylate
ROCK2, IC50: 105 nM
ROCK1, IC50: 24 μM
Selective Inhibitor
ROCK2-IN-2
ROCK2, IC50: 1 μM
  Selective Inhibitor
Chroman 1 dihydrochloride
ROCK2, IC50: 1 pM
ROCK1, IC50: 52 pM
Selective Inhibitor
Glycyl H-1152 hydrochloride
ROCKII, IC50: 11.8 nM
  Selective Inhibitor
ROCK-IN-1
ROCK2, IC50: 1.2 nM
  Selective Inhibitor
Y-27632 dihydrochloride
ROCK-II, Ki: 300 nM
ROCK-I, Ki: 220 nM
Pan Inhibitor ≥98.0%
Y-27632
ROCK-II, Ki: 300 nM
ROCK-I, Ki: 220 nM
Pan Inhibitor 99.91%
Fasudil Hydrochloride
ROCK2, IC50: 0.158 μM
p160ROCK, Ki: 0.33 μM
Pan Inhibitor ≥95.0%
RKI-1447 dihydrochloride
ROCK2, IC50: 6.2 nM
ROCK1, IC50: 14.5 nM
Pan Inhibitor
Ripasudil
ROCK2, IC50: 19 nM
ROCK1, IC50: 51 nM
Pan Inhibitor 99.75%
AT13148
ROCKII, IC50: 4 nM
ROCKI, IC50: 6 nM
Pan Inhibitor ≥98.0%
SAR407899
ROCK-2, IC50: 102 nM
ROCK-1, IC50: 276 nM
Pan Inhibitor 99.97%
GSK269962A
ROCK2, IC50: 4 nM
ROCK1, IC50: 1.6 nM
Pan Inhibitor ≥95.0%
Hydroxyfasudil
ROCK2, IC50: 0.72 μM
ROCK1, IC50: 0.73 μM
Pan Inhibitor 98.11%
ROCK inhibitor-2
ROCK2, IC50: 2 nM
ROCK1, IC50: 17 nM
Pan Inhibitor 99.59%
ROCK-IN-2
ROCK-2, IC50: 1.1 nM
ROCK-1, IC50: 0.6 nM
Pan Inhibitor 99.46%
RKI-1447
ROCK2, IC50: 6.2 nM
ROCK1, IC50: 14.5 nM
Pan Inhibitor 98.06%
BDP5290
ROCK2, IC50: 50 nM
ROCK1, IC50: 5 nM
Pan Inhibitor 98.79%
SAR407899 hydrochloride
ROCK-2, IC50: 102 nM
ROCK-1, IC50: 276 nM
Pan Inhibitor ≥98.0%
Rho-Kinase-IN-1
ROCK2, Ki: 3.9 nM
ROCK1, Ki: 30.5 nM
Pan Inhibitor 99.91%
SB-772077B dihydrochloride
ROCK2, IC50: 6 nM
ROCK1, IC50: 5.6 nM
Pan Inhibitor ≥99.0%
HSD1590
ROCK2, IC50: 0.51 nM
ROCK1, IC50: 1.22 nM
Pan Inhibitor 99.33%
Hydroxyfasudil hydrochloride
ROCK2, IC50: 0.72 μM
ROCK1, IC50: 0.73 μM
Pan Inhibitor 98.88%
Fasudil
ROCK2, IC50: 0.158 μM
p160ROCK, Ki: 0.33 μM
Pan Inhibitor
GSK269962A hydrochloride
ROCK2, IC50: 4 nM
ROCK1, IC50: 1.6 nM
Pan Inhibitor
Verosudil
ROCK2, Ki: 2 nM
ROCK1, Ki: 2 nM
Pan Inhibitor 99.66%
Ripasudil free base
ROCK2, IC50: 19 nM
ROCK1, IC50: 51 nM
Pan Inhibitor