2109704-99-4
2109704-99-4
Chemical Structure
Belumosudil mesylate
Synonym(s): KD025 mesylate; SLx-2119 mesylate
- CAS No.: 2109704-99-4
- Formula:C27H28N6O5S
- Molecular Weight:548.61
IUPAC Name: 2-(3-(4-((1H-indazol-5-yl)amino)quinazolin-2-yl)phenoxy)-N-isopropylacetamide methanesulfonate
InChIKey: ILQJXEIRBCHLOM-UHFFFAOYSA-N
SMILES: O=C(NC(C)C)COC1=CC=CC(C2=NC(NC3=CC4=C(NN=C4)C=C3)=C5C=CC=CC5=N2)=C1.OS(=O)(C)=O
Biological Activity: Belumosudil mesylate (KD025 mesylate) is a selective inhibitor of ROCK2 with IC50s of 105 nM and 24 μM for ROCK2 and ROCK1, respectively. Anti-fibrotic properties[1].
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Belumosudil mesylate | 99.89% | Belumosudil mesylate (KD025 mesylate) is a selective inhibitor of ROCK2 with IC50s of 105 nM and 24 μM for ROCK2 and ROCK1, respectively. Anti-fibrotic properties. | ||||||||||||||||||||
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Belumosudil mesylate (Standard) | ≥98% | Belumosudil (mesylate) (Standard) is the analytical standard of Belumosudil (mesylate). This product is intended for research and analytical applications. Belumosudil mesylate (KD025 mesylate) is a selective inhibitor of ROCK2 with IC50s of 105 nM and 24 μM for ROCK2 and ROCK1, respectively. Anti-fibrotic properties. | ||||||||||||||||||||
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References
