923359-38-0
Chemical Structure
SAR407899
- CAS No.: 923359-38-0
- Formula:C14H16N2O2
- Molecular Weight:244.29
IUPAC Name: 6-(piperidin-4-yloxy)isoquinolin-1(2H)-one
InChIKey: IPEXHQGMTHOKQV-UHFFFAOYSA-N
SMILES: O=C(NC=C1)C(C1=C2)=CC=C2OC3CCNCC3
Biological Activity: SAR407899 is a selective, potent and ATP-competitive ROCK inhibitor, with an IC50 of 135 nM for ROCK-2, and Kis of 36 nM and 41 nM for human and rat ROCK-2, respectively. SAR407899 shows stable inhibition of migrasome formation.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SAR407899 | 99.67% | SAR407899 is a selective, potent and ATP-competitive ROCK inhibitor, with an IC50 of 135 nM for ROCK-2, and Kis of 36 nM and 41 nM for human and rat ROCK-2, respectively. SAR407899 shows stable inhibition of migrasome formation. | ||||||||||||||||||||
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Similarity Score 0.98
HY-15687SAR407899 hydrochloride -
Similarity Score 0.65
HY-W098166Methyl 4-(piperidin-4-yloxy)benzoate hydrochloride -
Similarity Score 0.61
HY-146502PARP10/15-IN-3 -
Similarity Score 0.60
HY-143338ART-IN-1 -
Similarity Score 0.58
HY-161413Antibacterial agent 204 -
Similarity Score 0.58
HY-W129104Aripiprazole impurity 21 -
Similarity Score 0.58
HY-19172349U85 hydrochloride -
Similarity Score 0.58
HY-123138LY206130 free base -
Similarity Score 0.58
HY-14477UPF-1035 -
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