1. Cell Cycle/DNA Damage
    Epigenetics
  2. PARP
  3. ART-IN-1

ART-IN-1 

Cat. No.: HY-143338
Handling Instructions

ART-IN-1 (compound 7) is a selective PARP inhibitor with IC50s of 19, 22, 2.4, >100, 1.1 µM for PARP2, TNKS2, PARP10, PARP14, PARP15, respectively.

For research use only. We do not sell to patients.

ART-IN-1 Chemical Structure

ART-IN-1 Chemical Structure

CAS No. : 2418014-98-7

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Description

ART-IN-1 (compound 7) is a selective PARP inhibitor with IC50s of 19, 22, 2.4, >100, 1.1 µM for PARP2, TNKS2, PARP10, PARP14, PARP15, respectively[1].

IC50 & Target[1]

PARP15

1.1 μM (IC50)

PARP10

2.4 μM (IC50)

PARP2

19 μM (IC50)

TNKS2

22 μM (IC50)

PARP14

>100 μM (IC50)

In Vitro

ART-IN-1 (compound 7) (0-100 µM) shows inhibition of PARP2, TNKS2, PARP10, PARP14, PARP15 with IC50s of 19, 22, 2.4, >100, 1.1 µM, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

259.32

Formula

C14H13NO2S

CAS No.
SMILES

CC(OC1=CC2=C(C(NC3=C2C=CS3)=O)C=C1)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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