TNKS2/PARP5B

TNKS2/PARP5B Related Products (21):

By Type:	Pan (18) Selective (3)

Cat. No.	Product Name	Effect	Purity

HY-15147

XAV-939	Inhibitor	99.91%
XAV-939 is a Tankyrase inhibitor.

HY-12438

G007-LK	Inhibitor	99.42%
G007-LK is a potent and selective inhibitor of TNKS1 and TNKS2, with IC₅₀s of 46 nM and 25 nM, respectively.

HY-13990

NVP-TNKS656	Inhibitor	99.31%
NVP-TNKS656 is a highly potent, selective, and orally active TNKS2 inhibitor with IC₅₀ of 6 nM, and is > 300 fold selectivity against PARP1 and PARP2.

HY-100225

ME0328	Inhibitor	99.87%
ME0328 is a potent and selective ARTD3/PARP3 inhibitor with an IC₅₀ of 0.89±0.28 μM.

HY-16910

WIKI4	Inhibitor	99.93%
WIKI4 is a potent tankyrase inhibitor with an IC₅₀ of 26 nM for TNKS2.

HY-148566

OUL232	Inhibitor
OUL232 is a potent inhibitor of mono-ARTs PARP7, PARP10, PARP11, PARP12, PARP14, and PARP15.

HY-148753

PARP10-IN-2	Inhibitor
PARP10-IN-2 is a potent mono‐ADP‐ribosyltransferase PARP10 inhibitor with an IC₅₀ of 3.64 μM for human PARP10.

HY-W294889

OUL245	Inhibitor
OUL245 is a 7-Hydroxy derivative, and a selectively PARP2 inhibitor (IC₅₀=44 nM).

HY-122661

Mefuparib hydrochloride	Inhibitor	98.94%
Mefuparib hydrochloride (MPH) is an orally active, substrate-competitive and selective PARP1/2 inhibitor with IC₅₀s of 3.2 nM and 1.9 nM, respectively.

HY-12418

Stenoparib	Inhibitor	≥98.0%
E7449 is a potent PARP1 and PARP2 inhibitor and also inhibits TNKS1 and TNKS2, with IC₅₀s of 2.0, 1.0, ∼50 and ∼50 nM for PARP1, PARP2, TNKS1 and TNKS2, respectively, using ³²P-NAD⁺ as substrate.

HY-123892

RK-287107	Inhibitor	99.81%
RK-287107 is a potent and specific tankyrase inhibitor with IC₅₀s of 14.3 and 10.6 nM for tankyrase-1 and tankyrase-2, respectively.

HY-19351

MN-64	Inhibitor	99.73%
MN-64 is a potent tankyrase 1 inhibitor, with IC₅₀s of 6 nM, 72 nM, 19.1 μM, and 39.4 μM for TNKS1, TNKS2, ARTD1 and ARTD2, respectively.

HY-145267

OM-153	Inhibitor	99.59%
OM-153 is a potent and orally active tankyrase inhibitor with IC₅₀s of 13 nM and 2 nM for tankyrase 1 and tankyrase 2 (TNKS1/2), respectively.

HY-U00422

K-756	Inhibitor	99.76%
K-756 is a direct and selective tankyrase (TNKS) inhibitor, which inhibits the ADP-ribosylation activity of TNKS1 and TNKS2 with IC₅₀s of 31 and 36 nM, respectively.

HY-121719

TIQ-A	Inhibitor	99.65%
TIQ-A is a potent TNKS (poly-ART, PARP) inhibitor, with an IC₅₀ of 24 nM for TNKS2.

HY-147886

PARP1-IN-11	Inhibitor	98.58%
PARP1-IN-11 (compound 49) is a potent PARP1 inhibitor with IC₅₀ value of 0.082 µM.

HY-145266

OM-1700	Inhibitor
OM-1700 is a potent tankyrase inhibitor with IC₅₀s of 127 and 14 nM for tankyrase 1 and tankyrase 2, respectively.

HY-108516

TC-E 5001	Inhibitor
TC-E 5001 is an inhibitor of Wnt pathway that inhibits tankyrase 1/2 (TNKS1/2) via novel adenosine pocket binding, with K_ds of 79 nM and 28 nM, respectively.

HY-143338

ART-IN-1	Inhibitor
ART-IN-1 (compound 7) is a selective PARP inhibitor with IC₅₀s of 19, 22, 2.4, >100, 1.1 µM for PARP2, TNKS2, PARP10, PARP14, PARP15, respectively.

HY-146336

PARP1/2/TNKS1/2-IN-1	Inhibitor
PARP1/2/TNKS1/2-IN-1 (Compound I-9) is a dual PARP-1, PARP-2, TNKS1 and TNKS2 inhibitor with IC₅₀ values of 0.25 nM, 1.2 nM, 13.5 nM and 4.15 nM against PARP-1, PARP-2, TNKS1 and TNKS2, respectively.

Name
Email *

	Sorry, but the email address you supplied was invalid.