2. Cell Cycle/DNA Damage
    Epigenetics
  3. PARP
  4. PARP1-IN-11

PARP1-IN-11 

Cat. No.: HY-147886 Purity: 98.58%
COA Handling Instructions

PARP1-IN-11 (compound 49) is a potent PARP1 inhibitor with IC50 value of 0.082 µM. PARP1-IN-11 shows complete inhibition of PARP2 and substantially inhibits PARP3, TNKS1 and TNKS2.

For research use only. We do not sell to patients.

PARP1-IN-11 Chemical Structure

PARP1-IN-11 Chemical Structure

CAS No. : 2482484-87-5

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Based on 1 publication(s) in Google Scholar

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PARP PARP1 PARP2 PARP3 PARP4 TNKS1/PARP5A TNKS2/PARP5B PARP7 PARP10 PARP14 PARP15 PARP12 PARP16

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Description

PARP1-IN-11 (compound 49) is a potent PARP1 inhibitor with IC50 value of 0.082 µM. PARP1-IN-11 shows complete inhibition of PARP2 and substantially inhibits PARP3, TNKS1 and TNKS2[1].

IC50 & Target[1]

PARP1

0.082 μM (IC50)

PARP2

 

TNKS1

 

TNKS2

 

Molecular Weight

296.28

Appearance

Solid

Formula

C16H12N2O4
CAS No.
SMILES

O=C(C1=C(C(NC/2=O)=CC=C1)OC2=C/C3=CC=C(O)C=C3)N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Keywords:

PARP1-IN-112482484-87-5PARPpoly ADP ribose polymerasePARP11,4-benzodioxine1,4-benzoxazin-3-oneInhibitorinhibitorinhibit

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