1. Signaling Pathways
  2. Cell Cycle/DNA Damage
    Epigenetics
  3. PARP
  4. PARP Inhibitors

PARP Inhibitors

PARP

PARP1

PARP2

PARP3

PARP4

TNKS1/PARP5A

TNKS2/PARP5B

PARP7

PARP10

PARP14

PARP15

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

PARP Inducers, Inhibitors & Activators
Product Name PARP PARP1 PARP2 PARP3 PARP4 TNKS1/PARP5A TNKS2/PARP5B PARP7 PARP10 PARP14 PARP15 Purity
Olaparib  
PARP-1, IC50: 5 nM
PARP-2, IC50: 1 nM
   
tankyrase-1, IC50: 1.5 μM
          99.98%
XAV-939  
ARTD1, IC50: 5500 nM
ARTD2, IC50: 479 nM
   
TNKS1, IC50: 5 nM
TNKS2, IC50: 2 nM
        98.60%
Talazoparib  
PARP1, Ki: 1.2 nM
PARP2, Ki: 0.87 nM
                99.89%
Niraparib  
PARP-1, IC50: 3.8 nM
PARP-2, IC50: 2.1 nM
PARP-3, IC50: 1300 nM
V-PARP, IC50: 330 nM
TANK-1, IC50: 570 nM
          99.96%
Rucaparib  
PARP-1, Ki: 1.4 nM
                  99.84%
Veliparib  
PARP-1, Ki: 5.2 nM
PARP-2, Ki: 2.9 nM
                99.78%
RBN-2397              
PARP-7, IC50: 3 nM
PARP-7, Kd: 1 nM
      99.45%
Pamiparib
PARP
                    99.97%
PJ34
PARP, IC50: 110 nM
PARP-1, IC50: 110 nM
PARP-2, IC50: 86 nM
                98.01%
Niraparib tosylate  
PARP-1, IC50: 3.8 nM
PARP-2, IC50: 2.1 nM
PARP-3, IC50: 1300 nM
V-PARP, IC50: 330 nM
TANK-1, IC50: 570 nM
          99.97%
PJ34 hydrochloride
PARP, IC50: 110 nM
PARP-1, IC50: 110 nM
PARP-2, IC50: 86 nM
                99.10%
Dehydrocorydaline
PARP
                    99.77%
Fluzoparib  
PARP-1, IC50: 1.46±0.72  nM
                  99.84%
RBN012759        
PARP4, IC50: 10 μM
   
PARP7, IC50: 4 μM
PARP10, IC50: 1 μM
PARP14, IC50: <3 nM
  99.88%
AG14361  
PARP-1, Ki: 0.5 nM
                  99.44%
Rucaparib monocamsylate  
PARP-1, Ki: 1.4 nM
                  99.92%
G007-LK          
TNKS1, IC50: 46 nM
TNKS2, IC50: 25 nM
        99.42%
Niraparib hydrochloride  
PARP-1, IC50: 3.8 nM
PARP-2, IC50: 2.1 nM
PARP-3, IC50: 1300 nM
V-PARP, IC50: 330 nM
TANK-1, IC50: 570 nM
          99.76%
3-Aminobenzamide
PARP, IC50: 50 nM
                    99.16%
AZD-2461  
PARP1, IC50: 5 nM
PARP2, IC50: 2 nM
PARP3, IC50: 200 nM
              99.88%
NVP-TNKS656    
PARP2, IC50: 32 μM
     
TNKS2, IC50: 6 nM
        99.31%
Rucaparib phosphate  
PARP-1, Ki: 1.4 nM
                  99.76%
Iniparib  
PARP1
                  99.82%
NMS-P118  
PARP-1, Kd: 9 nM
PARP-2, Kd: 1390 nM
                99.78%
Veliparib dihydrochloride  
PARP-1, Ki: 5.2 nM
PARP-2, Ki: 2.9 nM
                99.96%
Venadaparib  
PARP1, IC50: 1.4 nM
PARP2, IC50: 1 nM
                98.03%
BGP-15
PARP, IC50: 120 μM
                    ≥98.0%
Paris saponin VII  
PARP-1
                  99.13%
GeA-69                  
PARP14, Kd: 2.1 μM
  99.97%
PARP14 inhibitor H10                  
PARP14, IC50: 490 nM
  98.16%
UPF 1069  
PARP-1, IC50: 8 μM
PARP-2, IC50: 0.3 μM
                99.20%
BYK204165  
hPARP-1, pIC50: 7.35
mPARP-2, pIC50: 5.38
                98.66%
OUL35                
ARTD10/PARP10, IC50: 329 nM
    99.84%
ME0328  
ARTD1/PARP1, IC50: 6.3 μM
ARTD2/PARP2, IC50: 10.8 μM
ARTD3/PARP3, IC50: 0.89 μM
 
ARTD5/TNKS1, IC50: 47.3 μM
ARTD6/TNKS2, IC50: 34.3 μM
 
ARTD10/PARP10, IC50: 71.3 μM
    99.87%
Mefuparib hydrochloride  
PARP1, IC50: 3.2 nM
PARP2, IC50: 1.9 nM
   
TNKS1, IC50: 1.6 μM
TNKS2, IC50: 1.3 μM
        98.94%
INO-1001
PARP
                    98.19%
A-966492  
PARP-1, Ki: 1 nM
PARP-2, Ki: 1.5 nM
                99.95%
RK-287107          
tankyrase-1, IC50: 14.3 nM
tankyrase-2, IC50: 10.6 nM
        99.81%
WIKI4            
TNKS2, IC50: 26 nM
        99.93%
PARP1-IN-5 dihydrochloride  
PARP-1, IC50: 14.7 nM
PARP-2, IC50: 0.9 μM
               
5,​7,​4'-​Trimethoxyflavone
PARP
                    99.78%
Niraparib (R-enantiomer)  
PARP-1, IC50: 2.4 nM
                  99.50%
(8R,9S)-Talazoparib  
PARP-1, IC50: 144 nM
                  98.36%
E7016
PARP
                    98.46%
MN-64  
ARTD1, IC50: 19.1 μM
ARTD2, IC50: 39.4 μM
   
TNKS1, IC50: 6 nM
TNKS2, IC50: 72 nM
        99.73%
SK-575  
PARP1
                 
PROTAC PARP1 degrader  
PARP1
                 
PARP10/15-IN-1                
PARP10, IC50: 160 nM
 
PARP15, IC50: 370 nM
1,5-Isoquinolinediol
PARP, IC50: 0.18-0.37 μM
                    99.33%
TIQ-A    
PARP2, IC50: 210 nM
     
TNKS2, IC50: 24 nM
 
PARP10, IC50: >10 μM
PARP14, IC50: >10 μM
PARP15, IC50: 230 nM
99.65%
OM-153          
TNKS1, IC50: 13 nM
TNKS2, IC50: 2 nM
        99.59%
PARP10/15-IN-2                
PARP10, IC50: 0.15 μM
 
PARP15, IC50: 0.37 μM
99.00%
DR2313  
PARP-1, IC50: 0.20 μM
PARP-2, IC50: 0.24 μM
                98.70%
PARP10/15-IN-3                
PARP10, IC50: 0.14 μM
 
PARP15, IC50: 0.40 μM
99.98%
PARP-1-IN-2  
PARP-1, IC50: 149 ± 11.0 nM
                  98.80%
5,7-Dihydroxychromone
PARP
                    99.98%
PARP1-IN-11  
PARP1, IC50: 0.082 μM
                 
K-756          
TNKS1, IC50: 31 nM
TNKS2, IC50: 36 nM
        99.76%
Niraparib tosylate hydrate  
PARP-1, IC50: 3.8 nM
PARP-2, IC50: 2.1 nM
PARP-3, IC50: 1300 nM
V-PARP, IC50: 330 nM
TANK-1, IC50: 570 nM
         
Rucaparib tartrate  
PARP-1, Ki: 1.4 nM
                 
Rucaparib camsylate  
PARP-1, Ki: 1.4 nM
                 
Simmiparib  
PARP1, IC50: 0.74 nM
PARP2, IC50: 0.22 nM
               
PARP1-IN-5  
PARP-1, IC50: 14.7 nM
PARP-2, IC50: 0.9 μM
               
Rucaparib acetate  
PARP-1, Ki: 1.4 nM
                 
Venadaparib hydrochloride  
PARP1, IC50: 1.4 nM
PARP2, IC50: 1 nM
               
PARP-2-IN-1    
PARP-2, IC50: 11.5 nM
               
PARP/PI3K-IN-1  
PARP-1, pIC50: 8.22
PARP-2, pIC50: 8.44
               
NMS-P515  
PARP-1, Kd: 16 nM
PARP-1, IC50: 27 nM (in Hela cells)
                 
Rucaparib hydrochloride  
PARP-1, Ki: 1.4 nM
                 
PARP1-IN-9  
PARP1, IC50: 30.51 nM
                 
PARP-2-IN-3    
PARP-2, IC50: 0.07 μM
               
EB-47  
ARTD1/PARP1, IC50: 45 nM
                 
OM-1700          
TNKS1, IC50: 127 nM
TNKS2, IC50: 14 nM
       
PARP1/BRD4-IN-1  
PARP1, IC50: 49 nM
                 
TC-E 5001          
TNKS1, Ki: 79 nM
TNKS2, Ki: 28 nM
       
ART-IN-1    
PARP2, IC50: 19 μM
     
TNKS2, IC50: 22 μM
 
PARP10, IC50: 2.4 μM
PARP14, IC50: >100 μM
PARP15, IC50: 1.1 μM
Verminoside  
PARP-1
                 
PARP1-IN-8  
PARP-1, IC50: 97 nM
                  99.29%
PARP7-IN-12              
PARP7, IC50: 7.836 nM
     
PARP1/BRD4-IN-2  
PARP1, IC50: 197 nM
                 
Anticancer agent 64
PARP
                   
Aviculin
PARP
                   
PARP/EZH2-IN-1  
PARP-1, IC50: 6.87 nM
                 
Anticancer agent 43  
PARP1
                 
PARP1-IN-10  
PARP1, IC50: 50.62 nM ([1])
                 
SK-575-NEG  
PARP-1, IC50: 2.64 nM
                 
PARP1/2/TNKS1/2-IN-1  
PARP-1, IC50: 0.25 nM
PARP-2, IC50: 1.2 nM
   
TNKS1, IC50: 13.5 nM
TNKS2, IC50: 4.15 nM
       
PARP-1/HDAC-IN-1  
PARP-1, IC50: 68.90 nM
                 
PARP1-IN-12  
PARP-1, IC50: 2.99 nM
                 
CEP-9722  
PARP-1, IC50: 20 nM
PARP-2, IC50: 6 nM
               
WD2000-012547  
PARP-1, pKi: 8.221